POSTDOCTORAL RESEARCH OPPORTUNITY AT EMORY UNIVERSITY



Funding is available to support a postdoctoral fellow for 2 years in the laboratory of Dr. Grace Pavlath in the Department of Pharmacology at Emory University in collaboration with Dr. Art English of the Department of Anatomy and Cell Biology.

The overall scope of the project involves the role of cytokines and other inflammatory peptides in temporomandibular disorders (TMDs). A combination of molecular, cellular, immunological and whole animal approaches are used to address questions relating to the etiology of the chronic muscle tenderness and pain in the masticatory muscles and/or temporomandibular joints found in these disorders. Elucidation of the role of inflammatory mediators in masticatory muscles is important for both understanding the etilogy of and designing novel therapeutic strategies for the treatment of TMDs.

This is a great opportunity to work in a young, energetic lab and apply basic molecular biological techniques to problems of disease mechanisms. Opportunities to learn and apply state- of-the-art gene transfer and imaging methods methods will be present. The major focus of the lab is the molecular and cellular biology of muscle. The lab is working on questions related to gene therapy, immunobiology of neuromuscular disease and skeletal muscle growth and regeneration.

The favorable climate and the dynamic and modern nature of the city of Atlanta should also make this position attractive. The successful candidate should possess a Ph.D. ( or DDS, M.D.) in Cell Biology, Immunology, Pathology or related experience. Preference will be given to candidates with neuromuscular or molecular biology backgrounds especially experience with in situ hybridization on tissue sections. Prefer US citizen or permanent resident.

Send curriculum vitae, brief summary of doctoral work, a statement of research interests, and three letters of reference to:

Dr. Grace Pavlath
Department of Pharmacology
Emory University
1510 Clifton Road, Atlanta, GA 30322


404-727-3353
gpavlath@bimcore.emory.edu

Emory University is an Afirmative Action/Equal Opportunity Employer.

Recent publications


Dhawan, J., L. C. Pan., G.K. Pavlath, M.A. Travis, A.M. Lanctot and H.M. Blau (1991)Systemic delivery of human growth hormone by injection of genetically engineered myoblasts. Science 254 : 1509-1512.

Gussoni, E., G.K. Pavlath, A.M. Lanctot, R.G. Miller, L. Steinman and H.M. Blau (1992) Normal dystrophin transcripts detected in DMD patients after myoblast transplantation. Nature 356: 345-348.

Blau, H.M., J. Dhawan and G.K. Pavlath (1993) Myoblasts in pattern formation and gene therapy. Trends in Genetics 9:269-274.

Gussoni, E., G.K. Pavlath, M. Powell, R.G. Miller, H.M. Blau and L. Steinman (1994) Secondary autoimmunity at the site of degenerative disease: Restricted TCR gene rearrangements in Duchenne muscular dystrophy. J. Immunol. 153: 4798-4805.

Pavlath, G.K., T.A. Rando and H.M. Blau (1994) Transient immunosuppressive treatment leads to long term retention of allogeneic myoblasts in hybrid myofibers. J. Cell Biol. 127: 1923-1932.

Rando, T. A., G. K. Pavlath and H.M. Blau (1995) The fate of myoblasts following transplantation into mature muscle. Exp. Cell Res. 220: 383-389.