Jim Bogenpohl

I’m originally from St. Charles, Missouri, and I went to undergrad at Washington University in St. Louis where I received a bachelor’s degree in biology in 2004. While at WU, I spent three years researching the mammalian circadian clock. Shortly after graduating, I joined Emory’s Neuroscience Program in the Fall of 2004. After a few rotations, I joined Yoland’s lab where I am currently studying new pharmacological treatments for Parkinson’s Disease involving antagonism of metabotropic glutamate receptors and adenosine receptors. I will also examine the cellular and sub-cellular localization of these receptors in the basal ganglia of monkeys using electron microscopy. Like a few other members of our lab, my project will involve a strong collaboration with the lab of Thomas Wichmann. I enjoy working with animals, and I spend a lot of time with the rhesus macaques here at the Yerkes Primate Center.
Publications
Book Chapters
Bogenpohl, JW and Y Smith (2009) Direct Pathway. In: The Encyclopedia of Movement Disorders (MOVE). Elsevier: Oxford, UK (in press).
Bogenpohl, JW and Y Smith (2009) Indirect Pathway. In: The Encyclopedia of Movement Disorders (MOVE). Elsevier: Oxford, UK (in press).
ABSTRACTS
Bogenpohl, J., A. Galvan, X. Hu, T. Wichmann and Y. Smith (2010) Electrophysiological and behavioral effects of group III mGluR agonists in MPTP-treated parkinsonian monkeys. FENS meeting, Amsterdam.
Masilamoni, G., D. Alagille, J. Bogenpohl, K. Delevich, V. Reddy, JR Votaw, G Tamagnan, A Galvan, T Wichmann and Y Smith (2009) Potential neuroprotective effects of metabotropic glutamate receptor 5 antagonist in MPTP-treated parkinsonian monkeys. Soc for Neurosci Abstr 828.17.
Bogenpohl J, J Pare, Y Smith (2008) Subcellular localization of the adenosine A2A receptor in the monkey basal ganglia. Soc Neurosci Abstr 825.23.
Boghenpohl JW, Pare JF and Smith Y (2007) Subcellular localization of adenosine A2A receptors in the striatum and globus pallidus of monkey and rat. IBAGS IXth Proceedings, Abstr P-056, p. 93.
J. W. Bogenpohl L, M. Verreault, A. Galvan, J. Liu, Y. Smith. The use of mGluR5 antagonists as antiparkinsonian therapy in MPTP-treated monkeys. Society for Neuroscience Abstracts, 175.3 (2006).
H. A. MitchellL, J. BogenpohlL, L. Liles, D. Bozyczko-Coyne, M. Williams, D. Weinshenker. Dopamine beta-hydroxylase (DBH) knockout mice support a dual dopaminergic-noradrenergic mechanism of modafinil (MOD) action. Society for Neuroscience Abstracts, 157.26 (2006).
RESEARCH PAPERS
Mitchell HA, Bogenpohl JW, Liles LC, Bozyczko-Coyne D, Williams M, Weinshenker D. Behavioral responses of dopamine beta-hydroxylase knockout mice to modafinil suggest a dual noradrenergic-dopaminergic mechanism of action. Pharmacol Biochem Behav. 2008 Dec;91(2):217-22.
Kozlov SV, Bogenpohl JW, Howell MP, Wevrick R, Panda S, Hogenesch JB, Muglia LJ, Van Gelder RN, Herzog ED, Stewart CL. The imprinted gene Magel2 regulates normal circadian output. Nat Genet. 2007 Oct;39(10):1266-72.
Slawson EE, Shaffer CD, Malone CD, Leung W, Kellmann E, Shevchek RB, Craig CA, Bloom SM, Bogenpohl J 2nd, Dee J, Morimoto ET, Myoung J, Nett AS, Ozsolak F, Tittiger ME, Zeug A, Pardue ML, Buhler J, Mardis ER, Elgin SC. Comparison of dot chromosome sequences from D. melanogaster and D. virilis reveals an enrichment of DNA transposon sequences in heterochromatic domains. Genome Biol. 2006;7(2):R15.