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Biosketch of Yoland Smith PhD

Primary Appointment

Professor
Dept of Neurology Emory University

Joint Appointment Associate Research Professor Yerkes National Primate Research Center

 

Current Administrative/Academic Appointments

2002-present: Primary: Professor, Dept Neurology, Emory Univ. Joint: Associate Research Professor, Yerkes

2004-present: Director, Graduate Program in Neuroscience, Emory University

2004-present: Chair, curriculum committee, Neuroscience Program, Emory University

2004-present: Chair, Faculty development committee, Dept Neurology, Emory University

2004-present: Member, Executive committee, graduate division of Biological and Biomedical Sciences

2007-present: Co-chair Neuroeducation committee, Emory Neuroscience initiative

2007-present:Member Faculty promotion committee, Dept Neurology, Emory University

2009-present: Council member, Executive committee, Laney Graduate School, Emory University

2009-present: Council member, Advisory committee, Postdoctoral Office, Emory University

1998-present: Member, Executive committee, Molecular Systems and Pharmacology Graduate Program

Previous Academic Appointments

1996-2002: Primary Appointment: Associate Professor, Dept of Neurology, Emory University

1991-1996: Assistant Professor, Dept of Anatomy, Laval University, Quebec, Canada

Previous Administrative Appointments

2004-present: Director, Graduate Neuroscience Program, Graduate School of Arts and Sciences, Emory University

2003-2004: Director Graduate Studies, Neuroscience Program, Emory University

2001-2002: President, Atlanta Chapter Society for Neuroscience

1999-2003: Chair Admission Committee Graduate Neuroscience Program, Emory University

1997-2004: Executive committee member, Graduate Neuroscience Program, Emory University

1997-2000: Executive committee member, Atlanta Chapter Society for Neuroscience

1997-1999: Executive committee member, admission committee, Graduate NS Program, Emory University

1998-2001: Executive committee member, Atlanta Chapter Society for Neuroscience

1992-1996: Executive committee member, Neurobiology Graduate Program, Laval University, Canada

1992-1996: Executive committee member, Admission committee, Neurobiology Graduate Program, Laval University, Canada

 

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Education/Training

INSTITUTION
AND LOCATION

DEGREE
FIELD OF STUDY
Laval University , Québec, Canada
BSc
Biology
Laval University , Québec, Canada
MSc
Neurobiology


Thesis title: Organization of the efferent projections of the substantia nigra in the squirrel monkey (Saimiri sciureus)

Supervisor: Dr Andre Parent, PhD

Laval University, Quebec, Canada
PhD Neurobiology

Thesis title: Neuroanatomical and Immunohistochemical studies of the basal ganglia in the squirrel monkey (Saimiri sciureus)

Supervisor: Dr Andre Parent, PhD

Post- Doctoral
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Dates
Position
Location
1991 Postdoctoral Fellow,
Department of Neurology
Supervisor: Dr. Mahlon DeLong

Emory University
Atlanta, Georgia

1990-1991 Postdoctoral Fellow,
Department of Neurology
Supervisor: Dr. Mahlon DeLong

Johns Hopkins University
Baltimore, Maryland

1987-1989 Postdoctoral Fellow, MRC Unit,
Department of Pharmacology
Supervisor: Dr. J. Paul Bolam
Oxford University
United Kingdom

Honors

 

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2006 ONE Award for Execellence in Dept and Institutional Initiatives, Dept Neurology, Emory University
2005 Apple Crystal Award for Excellence in Graduate Teaching, Emory University

 

Memberships


International Basal Ganglia Society (IBAGS) European Neuroscience Association (ENA) Brain Research Association (BRA), UK
International Brain Research Organization(IBRO)
American Society for Neuroscience
Brain Research Association (BRA), UK

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Grant Support

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Active :

Federally and non-federally funded

"Plasticity of striatal glutamatergic synapses in Parkinson's disease"
Principal Investigator: Yoland Smith, PhD
Agency: NIH/NINDS
Type: R01 (NS037948-14)
Project Period:2/01/2010-1/31/2014
The goal of this project is to elucidate various aspects of the synaptology and plasticity of the thalamostriatal system in normal and MPTP-treated parkinsonian monkeys.

"GABA-B Receptors and Parkinson's Disease"
Principal Investigator: Yoland Smith, PhD
Agency: NIH/NINDS
Type: R01 (NS42937)
Project Period: 4/01/2007-3/31/2012
This project aims at characterizing the localization and role of GABA-B receptors in the pre-synaptic modulation of glutamate release in primate basal ganglia. We also propose to test GABA-B agonists as potential therapeutic agents in parkinsonian monkeys"

"Training in Systems and Integrative Biology: Neuroscience"
Principal Investigator: Yoland Smith, PhD
Agency: NIH/NIGMS
Type: T32 GM08605-10
Project Period: 7/01/2006-6/30/2011
This is the training grant for the PhD neuroscience program at Emory University. This grant provides financial support and covers tuition fees for six students in the program.

"Udall Parkinson's Disease Center at Emory University: Circuitry to Therapy"
Principal Investigator: Yoland Smith, PhD
Agency: NIH/NINDS
Type: P50NS071669-01
Project Period: 7/1/2010-6/30/2015

"Extrastriatal Functions of Dopamine"
Principal Investigator: Thomas Wichmann, PhD
Agency: NIH/NINDS
Type: R01Ns071074-01
Project Period: 5/1/2010-4/30/2015

"MGluR4 as therapeutic targets in Parkinson's disease"
Principal Investigator: Yoland Smith, PhD
Agency: RJG Foundation
Project Period: 11/01/2008-10/31/2011
This project aims at testing the antiparkinsonian and electrophysiological effects of local administration of mGluR4 agonists in the striatum and globus pallidus of MPTP-treated parkinsonian monkeys.

"Early Cognitive Impairment in Parkinson's disease"
Principal Investigator: Yoland Smith, PhD
Agency: NCRR (Support of Yerkes National Primate Center Supplement)
Project Period: 11/01/2008-10/30/2010

"Thalamostriatal system in Parkinsonism"
Principal Investigator: Thomas Wichmann, PhD
Agency: NIH/NINDS
Type: RO1 NS062876
Project Period: 4/01/2009-3/31/2012

The goal of this project is to elucidate the role of the thalamostriatal system in regulating activity of cholinergic interneurons and projection neurons in normal and parkinsonian monkeys.

"Biomarkers for preclinical Parkinson's disease"
Principal Investigator: Jing Zhang, PhD
Agency: NIH/NINDS
Type: R01 NS057567
Project Period: 7/01/2008-10/31/2010
The goal of this project is to identify pre-clinical biomarkers for Parkinson's disease.

"PDZ scaffold regulation of astrocytic glutamate receptors and transporters"
Principal Investigator: Randy Hall, PhD
Agency: NIH/NINDS
Tpye: R01 NS055179
Project Period: 4/01/2008-3/31/2013
The goal of this project is to characterize the localization and function of various PDZ scaffold proteins in regulating astrocytic glutamate receptors and transporters.

"Mechanisms of Endosome Trafficking in Neurons"
Principal Investigator: Victor Faundez, PhD
Agency:NIH/NINDS
Type: R01 Ns042599
Project Period: 9/01/2008-8/31/2013
The goal of this proposal is to understand the protein interactions regulating endosome trafficking in neurons.

"Discovery of mGluR4 potentiators for symptomatic and disease-modifying treatment of PD"
Principal Investigator: Conn-Smith
Agency: Michael J Fox Foundation
Project Period: 12/1/2010-11/30/2011

"Evaluation of Prosavin for providing efficacy to MPTP lesioned rhesus monkeys"
Contract with Oxford Biomedical
Project Period: 4/23/2008-12/31/2010


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Graduate Program Teaching

2006-present: Course Director NS 551 (Techniques in Neuroscience, 1 cr), Graduate program in Neuroscience, Emory University (Total 30 hours).

2005-present: Course Director, IBS 506 (Basic Mechanisms of Neurological Diseases, 2cr), Graduate program in Neuroscience, Emory University (Total: 45 hours).

2004-present: Course Director and Lecturer of Neuroscience II (IBS 526, 7 credits) Graduate students, Emory University (21 hours lecture + attendance to all other lectures 60 hours + preparation of exams and course directorship).

1998-2004: Director and Lecturer of a Neuroanatomy course (IBS 533) to Neuroscience Graduate students, Emory University (21 hours lecture + attendance to all other lectures 16.5 hours + preparation of exams and course directorship).

2000-present: Lecturer in IBS 531-Principles of Molecular Therapeutics and Toxicology-(1 hour lecture)

Spring 1998: Lectures of Neuroanatomy (Course IBS 533) to Neuroscience Graduate students, Emory Univ. (4 hours).

1997-1998: Organization of the Seminar Class (NS-570R) for Graduate students in Neuroscience at Emory University (30 hours).

Fall 1994: Responsible for the organization of a course on basal ganglia for Graduate students in Neurobiology, Laval University, Quebec, Canada.

Special Graduate Teaching

December 2005: IBRO School of Neuroscience, Hong Kong Society of Neurosciences 2 days workshop on Imaging Techniques for Neurobiology “Pre- and Post-embedding Immunocytochemical Procedures to Study Receptors Localization in the Central Nervous System”.Hong Kong University of Science and Technology, Hong Kong.

Supervisory Teaching

Phd Students

2008- present: Abraham Mathai, Phd Graduate studies, Neuroscience Program, Emory University

2007-present: Kalynda Gonzales, Phd Graduate studies, Neuroscience Program, Emory University

2005-present: Jim Boghenpol, PhD Graduate studies, Neuroscience Program, Emory University

2005-2008: Alyssa Tippen, PhD graduate studies, BCDB Program, Emory University

2003-2008: Lily Ishkakov, PhD Graduate student Neuroscience Program, Emory University

2003-2008: Darlene Mitrano, PhD Molecular Systems and Pharmacology Program, Emory University.

2002-2006: Kelly Philpot, PhD Molecular Systems and Pharmacology Program, Emory University

2001-2006: Olga Poisik, PhD Graduate student Neuroscience Program, Emory University

2001-2006: Masaaki Kuwajima, Ph.D. Graduate student Neuroscience program, Emory University

2002-2005: Dinesh Raju, MD/PhD Program, Emory University

1998-2004: George W. Hubert, Ph.D. Graduate student Neuroscience program, Emory University

1998-2003: Jesse Hanson, Ph.D. Graduate student Neuroscience program, Emory University

1997-2001: Stephanie Dall Vechia, Ph.D. Graduate student MSP Program, Emory University

1993-1999: Mamadou Sidibé, Ph.D. student, Laval University, Quebec, Canada

1994-1997: Maryse Paquet, M. Sc;, Faculty of Medicine, Laval University, Quebec, Canada

1994-1996: Eric Shink, M. Sc., Faculty of Medicine, Laval University, Quebec, Canada

 

dr looking in a scope SELECTED PEER-REVIEWED MANUSCRIPTS

 

BIBLIOGRAPHY
.

(A) PUBLISHED AND ACCEPTED PEER-REVIEWED MANUSCRIPTS:

1. Parent, A., A. Mackey, Y. Smith and R. Boucher (1983) The output organization of the substantia nigra in the primate as revealed by retrograde double labeling method. Brain Res. Bull., 10:529-537.

2. Parent, A., C. Bouchard and Y. Smith (1984) The striatopallidal and striatonigral projections: two distinct fiber systems in primate. Brain Res., 330:385-390.

3. Smith, Y. and A. Parent (1984) Distribution of acetylcholinesterase-containing neurons in the basal forebrain and upper brainstem of the squirrel monkey ( Saimiri sciureus). Brain Res. Bull., 12:95-104.

4. Smith, Y., A. Parent, L. Kerkerian and G. Pelletier (1985) Distribution of neuropeptide Y-immunoreactivity in the basal forebrain and upper brainstem of the squirrel monkey ( Saimiri sciureus). J. Comp. Neurol., 236:71-89.

5. Smith, Y. and A. Parent (1986) Differential connections of caudate nucleus and putamen in the squirrel monkey ( Saimiri sciureus). Neuroscience, 18:347-371.

6. Smith, Y. and A. Parent (1986) Neuropeptide Y-immunoreactive neurons in striatum of cat and monkey: morphological characteristics, intrinsic organization and colocalization with somatostatin. Brain Res., 372:241-252.

7. Boegman, R.J., Y. Smith and A. Parent (1987) Quinolinic acid does not spare neuropeptide Y-immunoreactive neurons. Brain Res., 415:178-182.

8. Parent, A. and Y. Smith (1987) Differential dopaminergic innervation of the two pallidal segments in the squirrel monkey ( Saimiri sciureus). Brain Res., 426:397-400.

9. Parent, A. and Y. Smith (1987) Organization of efferent projections of the subthalamic nucleus in squirrel monkey as revealed by retrograde labeling methods. Brain Res., 436:296-310.

10. Smith, Y., A. Parent, P. Séguéla and L. Descarries (1987) Distribution of GABA-immunoreactive neurons in the basal ganglia of the squirrel monkey ( Saimiri sciureus). J. Comp. Neurol., 259:50-65.

11. Smith, Y., P. Séguéla and A. Parent (1987) Distribution of GABA-immunoreactive neurons in the thalamus of the squirrel monkey ( Saimiri sciureus). Neuroscience, 22:579-591.

12. Steriade, M., A. Parent, D. Paré and Y. Smith (1987) Cholinergic and non-cholinergic neurons of cat basal forebrain project to reticular and mediodorsal thalamic nuclei. Brain Res., 408:372-376.

13. Paré, D., Y. Smith, A. Parent and M. Steriade (1988) Projections of brainstem core cholinergic and non-cholinergic neurons of cat to intralaminar and reticular thalamic nuclei. Neuroscience, 25:69-87.

14. Parent, A., D. Paré, Y. Smith and M. Steriade (1988) Basal forebrain cholinergic and non-cholinergic projections to the thalamus and brainstem in cats and monkeys. J. Comp. Neurol., 277:281-302.

15. Smith, Y., D. Paré, M. Deschênes, A. Parent and M. Steriade (1988) Cholinergic and non-cholinergic projections from the upper brainstem core to the visual thalamus of cat. Exp. Brain Res., 70:166-180.

16. Smith, Y. and A. Parent (1988) Neurons of the subthalamic nucleus in primates display glutamate but not GABA immunoreactivity. Brain Res., 453:353-356.

17. Steriade, M., D. Paré, A. Parent and Y. Smith (1988) Projections of cholinergic and non-cholinergic neurons of the brainstem core to relay and associational thalamic nuclei in the cat and macaque monkey. Neuroscience, 25:47-69.

18. Lavoie, B., Y. Smith, J. Dumas and A. Parent (1989) Dopaminergic innervation of the basal ganglia in the squirrel monkey as revealed by tyrosine hydroxylase immunohistochemistry. J. Comp. Neurol., 289: 36-52.

19. Paré, D., Y. Smith, A. Parent and M. Steriade (1989) Neuronal activity of identified posterior hypothalamic neurons projecting to the brainstem peribrachial area of the cat. Neurosci. Lett., 107: 147-150.

20. Parent, A., Y. Smith, M. Filion and J. Dumas (1989) Distinct afferents to internal and external pallidal segments in the squirrel monkey. Neurosci. Lett., 96: 140-144.

21. Smith, Y. and J.P. Bolam (1989) Neurons of the substantia nigra reticulata receive a dense GABA-containing input from the globus pallidus in the rat. Brain Res., 493: 160-167.

22. Smith, Y., B. Lavoie, J. Dumas and A. Parent (1989) Evidence for a distinct nigropallidal dopaminergic projection in the squirrel monkey. Brain Res., 482: 381-386.

23. Bolam, J.P. and Y. Smith (1990) GABA- and Substance P-containing inputs to the dopaminergic neurones in the rat substantia nigra. Brain Res., 529: 57-78.

24. Smith, Y. and J.P. Bolam (1990) The output neurones and the dopaminergic neurones of the substantia nigra receive a GABA-containing input from the globus pallidus J. Comp. Neurol., 296: 47-64.

25. Smith, Y., J.P. Bolam and M. von Krosigk (1990) Topographical and synaptic organization of the GABA-containing pallidosubthalamic projection in the rat. Eur. J. Neurosci., 2: 500-511.

26. Smith, Y., L.-N. Hazrati and A. Parent (1990) Efferent projections of the subthalamic nucleus in the squirrel monkey as studied by the PHA-L anterograde tracing method. J. Comp. Neurol., 294: 306-323.

27. Smith, Y. and J.P. Bolam (1991) Convergence of synaptic inputs from the striatum and the globus pallidus onto identified nigrocollicular cells in the rat. A double anterograde labeling study. Neuroscience, 44: 45-75.

28. Bolam, J.P. and Y. Smith (1992) The striatum and the globus pallidus send convergent synaptic inputs onto single cells in the entopeduncular nucleus of the rat: A double anterograde labelling study combined with postembedding immunocytochemistry for GABA. J. Comp. Neurol., 321: 456-477.

29. Lapper, S.R., Y. Smith, A.F. Sadikot, A. Parent and J.P. Bolam (1992) Cortical input to parvalbumin-immunoreactive neurones in the putamen of the squirrel monkey. Brain Res., 580: 215-224.

30. Sadikot, A.F., A. Parent, Y. Smith and J.P. Bolam (1992) Efferent connections of the centromedian and parafascicular nuclei in primates. A light and electron microscopic study of the thalamostriatal projection in relation to striatal heterogeneity. J. Comp. Neurol., 320: 228-242.

31. Von Krosigk,M., Y. Smith, J.P. Bolam and A.D. Smith (1992) Synaptic organization of GABAergic inputs from the striatum and the globus pallidus onto neurons in the substantia nigra and retrorubral field which project to the medullary reticular formation. Neuroscience, 50: 531-549.

32. Paré, D. and Y. Smith (1993) The intercalated cell masses project to the central and medial nuclei of the amygdala in cats. Neuroscience 57: 1077-1090.

33. Paré, D. and Y. Smith (1993) Distribution of GABA immunoreactivity in the amygdaloid complex of the cat. Neuroscience 57: 1061-1076.

34. Smith, Y. (1993) The use of benzidine dihydrochloride as a substrate for immunohistochemical reactions at electron microscopic level. Neuroscience Protocols, 93-050-03-01-07.

35. Smith, Y. (1993) A double anterograde labelling method combining the use of PHA-L and biocytin at electron microscopic level. Neuroscience Protocols, 93-050-04-01-09.

36. Paré, D. and Y. Smith (1994) GABAergic projection from the intercalated cell masses of the amygdala to the basal forebrain in cats. J. Comp. Neurol. 344: 33-49.

37. Smith, Y., B.D. Bennett, J.P. Bolam, A. Parent and A.F. Sadikot (1994) Synaptic relationships between dopaminergic afferents and cortical or thalamic input at the single cell level in the sensorimotor territory of the striatum in monkey. J. Comp. Neurol. 344: 1-19.

38. Smith, Y. and D. Paré (1994) Intra-amygdaloid projections of the lateral nucleus in the cat: PHA-L anterograde labeling combined with post-embedding GABA and glutamate immunocytochemistry. J. Comp. Neurol. 342: 232-248.

39. Smith, Y., T. Wichmann and M.R. DeLong (1994) Synaptic innervation of neurones in the internal pallidal segment by the subthalamic nucleus and the external pallidum in monkey. J. Comp. Neurol. 343: 297-318.

40. Shink, E., and Y. Smith (1995) Differential synaptic innervation of neurones in the internal or the external segments of the globus pallidus by the GABA- and glutamate-containing terminals in the squirrel monkey. J. Comp. Neurol. 358: 119-141

41. Paré, D., Y. Smith and J.-F. Paré (1995) Intra-amygdaloid projections of the basolateral and basomedial nuclei in the cat: PHA-L anterograde tracing at the light and electron microscopic level. Neuroscience 69: 567-583.

42. Charara, A., Y. Smith, and A. Parent (1996) Glutamatergic inputs from the pedunculopontine nucleus to midbrain dopaminergic neurones in primates: PHA-L anterograde labelling combined with post-embedding glutamate and GABA immunohistochemistry. J. Comp. Neurol. 364: 254-266.

43. Smith, Y., A. Charara and A. Parent (1996) Synaptic innervation of midbrain dopaminergic neurones by glutamate-enriched terminals in the squirrel monkey. J. Comp. Neurol. 364: 231-253.

44. Sidibe, M. and Y. Smith (1996) Differential synaptic innervation of striatofugal neurones projecting to the internal or the external segments of the globus pallidus by thalamic afferents in the squirrel monkey. J. Comp. Neurol. 365: 445-465 .

45. Paquet, M., and Y. Smith (1996) Differential distribution of AMPA glutamate receptors in the two segments of the globus pallidus in monkeys. Eur. J. Neurosci. 8: 229-233.

46. Shink, E., M.D. Bevan, J.P. Bolam and Y. Smith (1996) The subthalamic nucleus and the external pallidum: Two tightly interconnected structures that control the output of the basal ganglia in primates. Neuroscience 73: 335-357.

47. Paré, D. and Y. Smith (1996) Thalamic collaterals of corticostriatal axons: Their termination field and synaptic targets in cats. J. Comp. Neurol. 372: 551-567.

48. Paquet, M., M. Tremblay, J.-J. Soghomonian and Y. Smith (1997) AMPA and NMDA glutamate receptor subunits in midbrain dopaminergic neurones in the squirrel monkey: An immunohistochemical and in situ hybridization study. J. Neurosci. 17: 1377-1396.

49. Pinault, D., Y. Smith and M. Deschênes (1997) Combined light and electron microscopic evidence for the lack of intrinsic axon collaterals and the existence of dendro-dendritic synapses in the thalamic reticular nucleus of the rat. J. Neurosci. 17: 3215-3233.

50. Sidibé, M., M.D. Bevan, J.P. Bolam and Y. Smith (1997) Efferent connections of the internal segment of the globus pallidus in the squirrel monkey: I. Topography and synaptic organization of the pallidothalamic projection. J. Comp. Neurol. 382: 323-347.

51. Shink, E., M. Sidibé and Y. Smith (1997) Efferent connections of the internal globus pallidus in the squirrel monkey: II. Topography and synaptic organization at the level of the pedunculopontine nucleus. J. Comp. Neurol. 382: 348-363.

52. Smith, Y., E. Koylu, P. Couceyro and M.J. Kuhar (1997) Ultrastructural localization of CART (Cocaine- and amphetamine-regulated transcript) peptides in the nucleus accumbens of monkeys. Synapse 27: 90-94.

53. Smith, Y., J.-F. Paré and D. Paré (1998) The intra-amygdaloid inhibitory network: Ultrastructural organization of parvalbumin-immunopositive elements. J. Comp. Neurol. 391: 164-179.

54. Paré, D. and Y. Smith (1998) Intra-amygdaloid connections: Similarities between rats and cats. Trends Neurosci. 21: 240-241.

55. Lambert, P.D., P.R. Couceyro, K.M. McGirr, S.E. Dall Vechia, N.C. Ling, E.B. DeSouza, Y. Smith and M.J. Kuhar (1998) CART peptides in the central control of feeding and interactions with Neuropeptide Y. Synapse 29: 293-298.

56. Couceyro, P., M. Paquet, E. Koylu, M.J. Kuhar and Y. Smith (1998) Cocaine- and Amphetamine-regulated transcript (CART) peptide immunoreactivity in myenteric plexus neurons of the rat ileum and co-localization with choline acetyltransferase. Synapse 30:
1-8.

57. Smith, Y. , E. Shink, M.D. Bevan and J.P. Bolam (1998) Synaptology of the direct and indirect striatofugal pathways. Neuroscience 86: 353-387.

58. Sidibé, M. and Y. Smith (1999) Thalamic inputs to striatal interneurones in monkeys: Synaptic organization and co-localization of calcium binding proteins. Neuroscience 89: 1189-1208.

59. Smith, Y. , J.E. Kieval, P.R. Couceyro and M.J. Kuhar (1999) CART peptide-immunoreactive neurones in the nucleus accumbens in monkeys: Ultrastructural analysis, co-localization studies and synaptic interactions with dopaminergic afferents. J. Comp. Neurol. 407: 491-501.

60. Charara, A. , E. Bkankstein and Y. Smith (1999) Presynaptic kainate receptors in corticostriatal terminals in monkeys. Neuroscience 91: 1195-1200.

61. Koylu, E.O., Y. Smith, P.R. Couceyro and M.J. Kuhar (1999) CART peptides colocalize with tyrosine hydroxylase neurons in rat locus coeruleus. Synapse 31: 309-311.

62. Hanson, J.E. and Y. Smith (1999) Group I metabotropic glutamate receptors at GABAergic synapses in monkeys. J. Neurosci. 19: 6488-6496.

63. Alagarsamy, S., S.T. Rouse, R.W Gereau IV, S.F. Heineman, Y. Smith and P.J. Conn (1999) Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems. Ann. NY. Acad. Sci. USA, 868: 526-530.

64. Freedman, L.J., T.R. Insel and Y. Smith (2000) Subcortical projections of the subgenual cortex (Area 25) of the macaque monkey. J. Comp. Neurol. 421: 172-188.

65. Charara, A. , C. Heilman, A.I. Levey and Y. Smith (2000) Pre- and post-synaptic localization of GABAB receptors in the basal ganglia in monkeys. Neuroscience 95: 127-140.

66. Dall Vechia, S., P.D. Lambert, P.C. Couceyro, M.J. Kuhar and Y. Smith (2000) CART peptide immunoreactivity in the hypothalamus and pituitary in monkeys: Analysis of ultrastructural features and interactions with neuropeptide Y in the paraventricular nucleus. J. Comp. Neurol. 416: 291-308.

67. Smith, Y., J.-F. Paré and D. Paré (2000) Differential synaptic innervation of parvalbumin-containing interneurons in the basolateral amygdaloid complex by cortical and and intrinsic amygdaloid connections. J. Comp. Neurol. 416: 496-508.

68. Paquet, M. and Y. Smith (2000) Presynaptic NMDA receptors in GABAergic terminals. J. Comp. Neurol. 433: 330-347.

69. Thomas, T.M., Y. Smith, A. I. Levey and S.M. Hersch (2000) Cortical inputs to m2-immunoreactive striatal interneurons in rat and monkey. Synapse 37: 252-261.

70. Kuhar, M.J., L.D. Adams, R.G. Hunter, S.Dall Vechia and Y. Smith (2000) CART peptides. Reg. Peptides 89: 1-6.

71. Smith, Y., A. Charara, J.R. Hanson, M. Paquet, and A.I. Levey (2000) GABA-B and group I metabotropic glutamate receptors in the striatopallidal complex in primates. J. Anatomy 196: 555-576.

72. Awad, H., G.W. Hubert, Y. Smith, A.I. Levey and P.J. Conn (2000) Activation of metabotropic glutamate receptor 5 has direct excitatory effects in neurons of the subthalamic nucleus and potentiates NMDA receptor currents. J. Neurosci. 20: 7871-7879.

73. Smith, Y. and J.Z. Kieval (2000) Striatal and extrastriatal dopaminergic innervation of the basal ganglia. Trends Neurosci. 23 (Suppl. Basal Ganglia, Parkinson’s Disease and levodopa therapy), S28-S33.

74. Baron, M.S., M. Sidibé, M.R. DeLong and Y. Smith (2001) Course of motor and associative pallidothalamic projections in monkeys. J. Comp. Neurol. 429: 490-501.

75. Hubert, G.W. , M. Paquet and Y. Smith (2001) Differential subcellular localization of mGluR1a and mGluR5 in the rat and monkey substantia nigra. J. Neurosci. 21: 1838-1847.

76. Dall Vechia-Adams, S., Y. Smith and M.J. Kuhar (2001) CART peptide-immunoreactive projection from the nucleus accumbens targets substantia nigra pars reticulata neurons in the rat. J. Comp. Neurol. 434: 29-39.

77. Smith, Y ., A. Charara, M. Paquet, J.Z. Kieval, J.E. Hanson, G.W. Hubert, M. Kuwajima, A.I. Levey (2001) Ionotropic and metabotropic GABA and glutamate receptors in the primate basal ganglia. J. Chem. Neuroanat. 22: 13-42.

78. Marino, M.J., S. Risso Bradley, M. Wittmann, G.W. Hubert, Y. Smith, and P.J. Conn (2001) Activation of the group I metabotropic glutamate receptor mGluR1 produces a direct excitation and mediates a slow EPSP in the substantia nigra pars reticulata. J. Neurosci. 21: 7001-7012.

79. Wittman, M., G.W. Hubert, Y. Smith and P.J. Conn (2001) Activation of metabotropic glutamate receptor 1 inhibits glutamatergic transmission in the substantia nigra pars reticulata. Neuroscience 105: 881-889.

80. Kieval, J.Z., G.W. Hubert, A. Charara, J.-F. Pare and Y. Smith (2001) Subcellular and subsynaptic localization of presynaptic and postsynaptic kainate receptor subunits in the monkey striatum. J. Neurosci. 21: 8746-8757.

81. Hanson, J.E. and Y. Smith (2002) Subcellular distribution of high-voltage-activated calcium channel subtypes in rat globus pallidus neurons. J. Comp. Neurol. 442: 89-98.

82. Dall Vechia-Adams, S. , M.J. Kuhar and Y. Smith (2002) Cocaine- and Amphetamine-regulated Transcript peptide projections in the ventral midbrain: Colocalization with gamma-aminobutyric acid, melanin-concentrating hormone, dynorphin and synaptic interactions with dopamine neurons. J. Comp. Neurol. 448: 360-372.

83. Sidibe, M., J.-F. Pare and Y. Smith (2002) Nigral and pallidal inputs to functionally segregated thalamostriatal neurons in the centromedian/parafascicular intralaminar nuclear complex in monkey. J. Comp. Neurol. 447: 286-299.

84. Alagarsamy, S., S.T. Rouse; C. Junge, G.W. Hubert, D. Gutman, Y. Smith and P.J. Conn (2002) NMDA-induced phosphorylation and regulation of mGluR5. Pharmacol. Biochem. Behavior 73: 299-306.

85. Marino, M.J., Smith, Y., and Conn , P.J. (2002) Therapeutic potential of metabotropic glutamate receptors in the basal ganglia. Current Drug Targets: CNS and Neurological Disorders. 1: 239-250.

86. Poisik, O.V., G. Mannaioni, S. Traynelis, Y. Smith and P.J. Conn (2003) Distinct functional roles of the metabotropic glutamate receptors 1 and 5 in the rat globus pallidus. J. Neurosci. 23:122-130.

87. Paquet, M. and Y. Smith (2003) Group I metabotropic glutamate receptors in the monkey striatum: Subsynaptic association with glutamatergic and dopaminergic afferents. J. Neurosci. 23: 7659-7669.

88. Galvan, A., Y. Smith and T. Wichman (2003) Continuous monitoring of intracerebral glutamate levels in awake monkeys using microdialysis and enzyme fluorometric detection. J. Neurosci. Methods 126: 175-185.

89. Kane-Jackson , R. and Y. Smith (2003) Pre-synaptic kainate receptors in GABAergic and glutamatergic terminals in the monkey globus pallidus. Neuroscience 122: 285-289.

90. Muly, E.C., M. Maddox and Y. Smith (2003) Distribution of mGluR1a and mGluR5 immunolabeling in primate prefrontal cortex. J. Comp. Neurol. 467: 521-535.

91. Muly, E.C., Y. Smith, P.Allen and P. Greengard (2004) Subcellular distribution of spinophilin immunolabeling in primate prefrontal cortex: Localization to and within dendritic spines. J. Comp. Neurol. 469: 185-197.

92. Hanson, J.E., Y. Smith and D. Jaeger (2004) Sodium channels and dendritic spike initiation at excitatory synapses in globus pallidus neurons. J. Neurosci. 24: 329-340.

93. Kuwajima, M., R.A. Hall and Y. Smith (2004) Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the monkey subthalamic nucleus. J. Comp. Neurol. 474: 589-602.

94. Hubert, G.W. and Y. Smith (2004) Age-related changes in the expression of pre-synaptic and glial group I mGluRs in the rat substantia nigra pars reticulata. J. Comp. Neurol. 475: 95-106.

95. Charara, A., A. Galvan, M. Kuwajima, R.A. Hall and Y. Smith (2004) An electron microscopic immunocytochemical study of GABAB R2 receptors in the monkey basal ganglia: A comparative analysis with GABAB R1 receptors distribution. J. Comp. Neurol. 476: 65-79.

96. Galvan, A., A. Charara, J.-F. Pare, J.M. Fritschy, A.I. Levey and Y. Smith (2004) Differential subsynaptic llocalization of GABA-A and GABA-B receptors in the primate subthalamic nucleus. Neuroscience 127: 709-721.

97. Smith, Y. , D. Raju, J.-F. Pare and M. Sidibe (2004) The thalamostriatal system: A highly specific network of the basal ganglia circuitry. Trends in Neurosci. 27: 520-527.

98. Charara, A., J.-F. Pare, A.I. Levey and Y. Smith (2005) Synaptic and extrasynaptic GABA-A and GABA-B receptors in the globus pallidus: An electron microscopic immunogold analysis in monkeys. Neuroscience 131: 917-933.

99. Philpot, K., Y. Smith and M.J. Kuhar (2005) A CART peptide projection from the lateral hypothalamus to the ventral tegmental area. Neuroscience 135: 915-925.

100. Mazloom, M. and Y. Smith (2006) Synaptic microcircuitry and GABA immunoreactivity of tyrosine hydroxylase-containing neurons and terminals in the striatum of MPTP-treated monkeys. J. Comp. Neurol. (in press).

101. Poisik, O., D. Raju, M. Verreault, A. Rodriguez, O.A. Abeniyi, P.J. Conn and Y. Smith (2005) Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus. Neuropharmacology 49: 57-69.

102. Fam, S.R., M. Paquet, A.M. Castleberry, H. Oller, J. Lee, S.F. Traynelis, Y. Smith, C.C. Yun and R.A. Hall (2005) P2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2. PNAS 102: 8042-8047.

103. Bordelon, J., Y. Smith, A. Nairn, R.J. Colbran, P. Greengard and E.C. Muly (2005) Differential localization of protein phosphatase-1 a,b and g 1 isoforms in primate prefrontal cortex. Cerebral cortex di1 10.1093: pp. 1-10.

104. Galvan, A., R. Villalba, S. West, N. Maidment, L. Ackerson, Y. Smith and T. Wichmann (2005) GABAergic modulation of the activity of globus pallidus neurons in primates: An in vivo analysis of GABA-A, GABA-B and GABA transporters function. J. Neurophysiol. 94: 990-1000.

105. Jin, X.-T. and Y. Smith (2006) Localization and function of pre and postsynaptic kainate receptors in the rat globus pallidus. Eur. J. Neurosci. 23: 374-386.

106. Paquet, M., M. Kuwajima, C.C. Yun, Y. Smith and R.A. Hall (2006) Astrocytic and neuronal localization of the scaffold protein NHERF-2 in mouse brain. J. Comp. Neurol. 494: 752-762.

107. Raju, D.V. and Y. Smith (2006) Anterograde Axonal Tracing. Curr. Proto. Neurosci.

108. Villalba,R., D.V. Raju and Y. Smith (2006) GABAB receptors in the centromedian/parafascicular thalamic nuclear complex: An ultrastructural analysis of GABA BR1 and GABABR2 in the monkey thalamus. J. Comp. Neurol. 496:269-287.

109. Philpot, K and Y Smith (2006) CART peptide and the mesolimbic dopamine system. Neuropeptides.

110. Raju DV, DJ Shah, TM Wright and Y Smith (2006) Differential synaptology of vGluT2-containing thalamostriatal afferents between the patch and matrix compartments in rats. J. Comp. Neurol.499: 231-243.

111. Borges, K., H. Irier, D. McDermott, R. Dingledine and Y. Smith (2006) Degeneration and proliferation of astrocytes in the mouse dentate gyrus after pilocarpine-induced status epilepticus. Exp. Neurol 201: 416-423.

112. Bough, KJ, J Wetherington, B Hassel, JF Pare, J Gawryluk, JG Greene, R Shaw, Y Smith, JD Geiger and RJ Dingledine (2006) Mitochondrial biogenesis induced by ketogenic diet in rat hippocampus. Ann. Neurol 60: 223-235.

113. Galvan, A., M. Kuwajima and Y. Smith (2006) Glutamate and GABA Receptors in the basal ganglia: What does their Subsynaptic Localization Reveal about their Functions? Neuroscience 143: 351-375.

114. Paquet, M, MJ Asay, SR Fam, AM Castleberry, H Oller, Y Smith, CC Yun, SF Traynelis and RA Hall (2006) The PDZ scaffold NHERF-2 interacts with mGluR5 and regulates receptor activity. J. Biol. Chem 281: 29949-29961.

115. Elfenbein, HA, RF Rosen, SL Stephens, RC Switzer, Y Smith, J Pare, R Warzok and L Walker (2007) Cerebral b -amyloid angiopathy in aged squirrel monkeys.

116. Mitrano, D.J. and Y. Smith (2007) A comparative analysis of mGluR1a and mGluR5 in the shell and core of the rat and monkey accumbens. J. Comp. Neurol. 500: 788-806.

117. Bough, KJ, M Paquet, JF Pare, B Hassel, Y Smith, RA Hall and R Dingledine (2007) Evidence against enhanced glutamate transport in the anticonvulsant mechanism of the ketogenic diet. Epilepsy Res. 74: 232-236

118. Bonsi, P., G. Sciamanna, D.A. Mitrano, D. Cuomo, G. Bernardi, P. Platania, Y. Smith and A. Pisani (2007) Functional and ultrastructural analysis of group I mGluRs in striatal fast-spiking interneurons. Eur. J. Neurosci. 25: 1319-1331.

119. Ruju DV and Y. Smith (2007) Anterograde axonal tract tracing. Curr. Proto. In Neurosci.

120. Kuwajima, M, MD Dehoff, T Furuicchi, PF Worley, RA Hall and Y Smith (2007) Localization and expression of group I metabotropic glutamate receptors in the mouse globus pallidus and subthalamic nucleus: Regulatory effects of MPTP treatment and constitutive Homer deletion. J. Neurosci. 27: 6249-626

121. Poisik, OV, MJ Marino, Y Smith and PJ Conn (2007) D1 and D2-like dopamine receptors regulate signaling properties of group I metabotropic glutamate receptors in the rat globus pallidus. Eur. J. Neurosci. 26: 852-862.

122. Kliem M, NT Maidment, LC Ackerson, Y Smith and T Wichmann (2007) Activation of nigral and pallidal dopamine D1-like receptors modulates basal ganglia outflow in monkeys. J Neurophysiol 98: 1489-1500.

123. Jin XT and Y Smith (2007) Activation of presynaptic kainate receptors suppresses GABAergic synaptic transmission in the rat globus pallidus. Neuroscience.

124.Smith, Y. and R. Villalba (2007) Striatal and extrastriatal dopamine in the basal ganglia: An overview of its anatomical organization in normal and parkinsonian brains. Mov. Disorders.

125.Raju DV, TH Ahern, DJ Shah, TM Wright, DG Standaert, RA Hall, Y Smith (2007) Differential synaptic plasticity of the corticostriatal and thalamostriatal systems in MPTP-treated monkey model of Parkinson’s Disease. Eur J Neuroscience.

126.Grabowska, D, M Jayaraman, KM Kaltenbronn, SL Sandiford, Q Wang, S Jenkins, VZ Slepak, Y Smith and KJ Blumer (2007) Synaptic maturation involved the postnatal induction and synaptic localization of G protein regulatory complexes containing RGS7 family member, Gb5 and R7BP. Neuroscience.

127.Tippen, AL, JF Pare, N Langwieser, S Moosmang, TA Milner, Y Smith and A. Lee (2007) Ultrastructural evidence for pre- and post-synaptic localization of Cav 1.2 L-type Ca+2 channels in the rat hippocampus. J. Comp. Neurol.

128. Raju DV, DJ Shah, TM Wright, DG Standaert, RA Hall, Y Smith (2008) Differential synaptic plasticity of the corticostriatal and thalamostriatal systems in MPTP-treated monkey model of Parkinson's Disease. Eur J Neuroscience 27: 1647-1658, PMID: 18428632.

129. Tippens AL, JF Pare, N Langwieser, S Moosmang, T Milner, Y Smith and A Lee (2008) Ultrastructural evidence for pre-and postsynaptic localization of Cav 1.2 type Ca2+ channels in the rat hippocampus. J Comp Neurol 506: 569-583.

130. Smith Y and R Villalba (2008) Striatal and extrastriatal dopamine in the basla ganglia. An overview of its anatomical organization in normal and parkinsonian brains. Mov Disorders 23, Suppl 3: S534-547, PMID 18781680.

131. Lanciego, JL, MC Rodriguez-Oroz, FJ Blesa, L Alvarez-Erviti, J Guridi, Y Smith and JA Obeso (2008) Lesion of the centromedian thalamic nucleus in MPTP-treated primates. Mov Disorders 23: 708-715. PMID: 18175345.

132. Grabowska, D, M Jayaraman, KM Kaltenbronn, SL Sandiford, Q Wang, S Jenkins, V Slepak, Y Smith and KJ Blumer (2008) Postnatal induction and localization of R7BP, a membrane-anchoring protein for RGS7 family-Gb5 complexes in brain. Neuroscience 151: 969-982. PMID: 18248908

133.Yang, SH et al. (2008) Towards a transgenic model of Huntington’s disease in nonhuman primates. Nature 453: 921-924, PMID: 18488016.

134. Rubio ME, KA Gudsnuk, Y Smith and DK Ryugo (2008) Revealing the molecular layer of the primate dorsal cochlear nucleus. Neuroscience 154: 99-113, PMID: 18222048

135.Mitrano, D, C. Arnold and Y Smith (2008) A comparative analysis of the subcellular and subsynaptic localization of group I mGluRs in the nucleus accumbens of normal and cocaine-treated rats. Neuroscience 154: 653-666, PMID: 18479833

136. Villalba R, H Lee and Y Smith (2009) Dopaminergic denervation and spine loss in the striatum of MPTP-treated monkeys. Exp. Neurol 215: 220-227, PMID: 18977221

137. Smith, Y., D. Raju, B. Nanda, JF Pare, A Galvan and T Wichmann (2009) The thalamostriatal systems: Anatomical and functional organization in normal and parkinsonian states. Brain res Bull 78: 60-68, PMID: 18805468

138. Rommelfanger, K.S., D.A. Mitrano, Y. Smith and D. Weinshenker (2009) Light and electron microscopic localization of alpha 1 adrenergic receptor in the rat striatum and ventral midbrain. Neuroscience 158: 1530-1540, PMID: 19068224

139. Nanda B, A. Galvan, Y Smith and T Wichmann (2009) Effects of stimulation of the centromedian nucleus of the thalamus on the activity of striatal cells in awake rhesus monkeys. Eur J Neurosci 29: 588-598. PMID: 19175404

140. Newell-Litwa, K., G. Salazar, Y Smith and V Faundez (2009) Roles of BLOC-1 and AP-3 complexes in Cargo sorting to synaptic vesicles. Mol Biol Cell 20: 1441-1453, PMID 19144828.

141. Kliem, M.A., J.-F. Pare, Z.U. Khan, T. Wichmann and Y. Smith (2009) Comparative ultrastructural analysis of D1 and D5 dopamine receptor distribution in the substantia nigra and globus pallidus of monkeys. Adv. Behav. Biol. 58: 239-253. PMID. 19750130

142. Ross H.E., C.D. Cole, Y. Smith, I.D. Neumann, R. Landgraf, A.Z. Murphy and L.J. Young (2009) Characterization of the oxytocin system regulating affiliative behavior in female prairie voles. Neuroscience 162: 892-903. PMID. 19482070

143. Mitrano, D.A., J.-F. Pare and Y. Smith (2010) Ultrastructural relationships between cortical, thalamic and amygdala glutamatergic inputs and group I metabotropic glutamate receptors in the rat accumbens. J. Comp. Neurol. 518: 1315-1329. PMID 20151362.

144. Lee, H., HL Melrose, JF Pare, MJ Farrer and Y Smith (2010) Lrrk2 localization in the primate basal ganglia and thalamus: A light and electron microscopic analysis in monkeys. Exptl Neurology 224: 438-447. PMID 20483355.

145. Smith, Y., RM Villalba and DV Raju (2009) Striatal spine plasticity in Parkinson’s disease: Pathological or not? Parkinsonism and Related Disorders (in press).

146. Newell-Litwa, K., S. Chintala, S. Jenkins, J.-F. Pare, L. McGaha, Y. Smith and V. Faundez (2010) Hermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampus. J. Neurosci. 30: 820-831. PMID 20089890.

147. Kleim, M., J-F Pare, Z. Khan, T. Wichmann and Y. Smith (2010) Ultrastructural localization of dopamine D1- like receptors in the substantia nigra pars reticulate and the internal segment of the globus pallidus in parkinsonian monkeys. Eur. J. Neurosci. 31: 836-851. PMID 20374284.

148. Galvan, A., X. Hu, Y. Smith and T. Wichmann (2010) Localization and function of GABA transporters in the globus pallidus of parkinsonian monkeys. Exptl Neurology 223: 505-515. PMID 20138865.

149. Masilamoni, G., J. Votaw, L. Howell, R. Villalba, M. Goodman, RJ Voll, J. Stehouwer, T. Wichmann and Y. Smith (2010) 18F-FECNT: Validation as PET dopamine transporter ligand in parkinsonism. Exptl Neurology (in press).

150. Lee, S., S. Simons, S. Heldt, M. Zhao, J. Schroeder, C. Vellano, D. Cowan, S. Ramineri, C. Yates, Y. Feng, Y. Smith, JD Sweatt, D. Weinshenker, K. Ressler, S. Dudek and J. Hepler (2010) RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory. PNAS (in press).

151. Villalba, RM and Y. Smith (2010) Differential structural plasticity of corticostriatal and thalamostriatal axo-spinous synapses in MPTP-trataed parkinsonian monkeys. J. Comp. Neurol. (in press).

(B) MANUSCRIPTS SUBMITTED FOR PUB LICATION:

152. Redgrave, P., M. Rodriguez, Y. Smith, M.C. Rodriguez-Oroz, S. Lehericy, H. Bergman, Y. Agid, M.R. DeLong, J.A. Obeso (2010). Dual functional organization of the basal ganglia: Differential impairment in Parkinson's disease Nature Reviews Neuroscience (submitted).

153. Jin, X., JF Pare and Y. Smith (2010) Differential localization and function of GABA transporters, GAT-1 and GAT-3, in the rat globus pallidus. Eur J. Neurosci. (submitted).

(C) SYMPOSIUM CONTRIBUTIONS:

154. Parent, A., Y. Smith and L. De Bellefeuille (1984) The output organization of the pallidum and substantia nigra in primate. In: The Basal Ganglia - Structure and Function, Advances in Behavioral Biology, J.S. McKenzie (Ed.) Plenum Press, 27:147-160.

155. Parent, A., Y. Smith and M.-Y. Arsenault (1987) Chemical anatomy of the basal ganglia in primate. In: The Basal Ganglia - Structure and Function II, M.B. Carpenter and A. Jayaraman (Eds.) Plenum Press, New York, pp. 3-41.

156. Parent, A., L.-N. Hazrati and Y. Smith (1989) The subthalamic nucleus in primates. A neuroanatomical and immunohistochemical study. In: Neural mechanisms in disorders of movement, A.R. Crossman and M.A. Sambrook (eds), John Libbey, London, pp. 29-35.

157. Bolam, J.P. and Y. Smith (1991) Characterization of the synaptic inputs to the dopaminergic neurones in the rat substantia nigra. In: The Basal Ganglia III; G. Bernardi, M.B. Carpenter, G. Di Chiara, M. Morelli and P. Stanzione (eds), Plenum Press, New York, pp. 117-129.

158. Bolam, J.P., Y. Smith, C.A. Ingham, M. von Krosigk and A.D. Smith (1993) Convergence of synaptic terminals from the striatum and the globus pallidus onto single neurones in the substantia nigra and the entopeduncular nucleus. In: Chemical Signalling in the Basal Ganglia (G.W. Arbuthnott and P.C. Emson eds). Prog. Brain Res. 99: 73-88. Elsevier: Amsterdam.

159. Smith, Y. , T. Wichmann and M.R. DeLong (1994) The external pallidum and the subthalamic nucleus send convergent synaptic inputs onto single neurones in the internal pallidal segment in monkey: Anatomical organization and functional significance. In: The Basal Ganglia IV: New ideas and data on structure and function, (G. Percheron, J.S. McKenzie and J. Féger eds). Plenum Press: New York, pp. 51-62.

160. Sadikot, A.F., T.M. Rudkin and Y. Smith (1996) The amygdalostriatal projection: An analysis of synaptic inputs to GABAergic interneuron subtypes. In C. Ohye, M. Kimura and J. McKenzie (eds). Basal Ganglia V. Plenum Press: New York, pp. 33-42.

161. Smith, Y ., A. Charara, J.E. Hanson, W.G. Hubert and M. Kuwajima (2001) Chemical anatomy and synaptic connectivity of the globus pallidus and subthalamic nucleus. In Ilinsky, I.A. and K. Kultas-Ilinsky (eds), “Basal Ganglia and Thalamus in Health and Movement Disorders”, Plenum Press: New York, pp. 119-134.

162. Poisik, O., Y. Smith and P.J. Conn (2002) Metabotropic glutamate receptors in the globus pallidus. In Faull, R.L.M. and Nicholson, L. (eds) “Basal Ganglia VII”. Plenum Press: New York, pp. 409-420.

163. Sidibe, M., J.-F. Pare and Y. Smith (2002) Anatomical and functional relationships between intralaminar thalamic nuclei and basal ganglia in monkeys. In Faull, R.L.M. and Nicholson, L. (eds) “Basal Ganglia VII”. Plenum Press: New York, pp. 233-242.

164. Smith, Y., J.E. Hanson, M. Paquet and W.G. Hubert (2003) Synaptic localization of metabotropic glutamate receptors in the monkey basal ganglia. In A.M. Graybiel, M.R. DeLong and S.T. Kitai (eds), Basal Ganglia VI, Plenum Press: New York, pp. 567-580.

165. Charara, A ., M. Paquet, J.D. Rothstein and Y. Smith (2003) Subcellular and subsynaptic localization of glutamate transporters in the monkey basal ganglia. In A.M. Graybiel, M.R. DeLong and S.T. Kitai (eds), Basal Ganglia VI, Plenum Press: New York, pp. 599-613.

166. Jin, XT and Y. Smith (2005) Localization and functions of kainate receptors in the rat globus pallidus. In Bolam, JP et al (eds), IBAGS VIIIth, Plenum press, New York, pp. 131-140.

167. Raju, DV and Y. Smith (2005) Differential localization of vesicular glutamate transporters 1 and 2 in the rat striatum. In Bolam, JP et al (eds), IBAGS VIIIth, Plenum press, New York, pp. 601-610.

168. Galvan, A., M.A., Kliem, Y. Smith and T. Wichmann (2005) GABAergic and dopaminergic modulation of basal ganglia output in primates. In Bolam, JP et al (eds), IBAGS VIIIth, Plenum press, New York, pp. 575-584.

169.Galvan, A., B. Nanda, X. Hu, Y. Smith and T. Wichmann (2009) Changes in the subcellular localization and functions of GABA-B receptors in the globus pallidus of MPTP-treated monkeys.  In Groenewegen HJ et al (eds), The Basal Ganglia IX, Springer: New York, pp. 387-397.

170. Kliem, MA, J-F. Pare, Z.U. Khan, T. Wichmann and Y. Smith (2009) Comparative ultrastructural analysis of D1 and D5 dopamine receptor distribution in the substantia nigra and globus pallidus of monkeys. In Groenewegen HJ et al (eds), The Basal Ganglia IX, Springer: New York, pp. 239-253.

171. Jin, XT, J-F. Pare and Y. Smith (2009) Blockade of GABA transporter (GAT-1) modulates GABAergic transmission in the rat globus pallidus. In Groenewegen HJ et al (eds), The Basal Ganglia IX, Springer: New York, pp. 297-307.

172. Villalba, R., H. Lee, D. Raju and Y. Smith (2009) Striatal dopaminergic denervation and spine loss in MPTP-treated monkeys. In Groenewegen HJ et al (eds), The Basal Ganglia IX, Springer: New York, pp.361-375.

(D) BOOK CHAPTERS:

173. Parent, A., B. Lavoie, Y. Smith and P. Bédard (1990) The dopaminergic nigropallidal projection in primates: distinct cellular origin and relative sparing in MPTP-treated monkeys. In: Advances in Neurology; Parkinson's disease. Anatomy, Pathology and Therapy; M.B. Youdim, A.D. Korczyn, E. Melamed and M.B.H. Youdim (eds), Raven Press: New York, Vol. 53: 111-116.

174. Smith, Y. (1992) Anterograde tracing with PHA-L and biocytin at the electron microscopic level. In Bolam, J.P. (ed.). Practical approach series; "Experimental neuroanatomy: A practical approach". Oxford University Press, Oxford, UK, pp. 61-79.

175. Smith, Y. and J.P. Bolam (1992) Combined approaches to experimental neuroanatomy: combined tracing and imunocytochemical techniques for the study of neuronal microcircuits. In Bolam, J.P. (ed.). Practical approach series; "Experimental Neuroanatomy: A practical approach". Oxford University Press, Oxford, UK, pp. 239-266.

176. Smith, Y. , E. Shink and M. Sidibé (1998) Neuronal circuitry and synaptic connectivity of the basal ganglia. In "Neurosurgery Clinics of North America: Surgical Treatment of Movement Disorders". Edited by Roy A.E. Backay. W.B. Saunders Company, Philadelphia, 9: 203-222.

177. Charara, A., M. Sidibe and Y. Smith (2003) Basal ganglia circuitry and synaptic connectivity. In Tarsy, D., Vitek, J.L. and Lozano, A. (eds). “Surgical Treatment of Parkinson’s Disease and Other Movement Disorders”. The Humana Press: Totowa, NJ, pp. 19-39.

178. Smith, Y. and A. Charara (2003) Anatomy and synaptic connectivity of the basal ganglia. In K.J. Burchiel and R.E. Bakay (eds), Youmans Neurological Surgery, 5 th ed., W.B. Saunders Company: Philadelphia, pp. 2683-2698.

179. Wichmann, T., Y. Smith and J.L. Vitek (2003) Basal ganglia anatomy and physiology. In “Parkinson’s Disease at the Millennium”, Factor, S.A. and W.J. Weiner (eds). Demos Vermande, pp. XXX.

180. Smith, Y. (2003) Functional anatomy of the basal ganglia. In “Encyclopedia of the Neurological Sciences”, edited by Aminoff, M.J. and Daroff, R.B. Academic Press, San Diego, pp. 345-355.

181. Smith, Y. and M. Sidibe (2003) The Thalamus. In (P.M. Conn, ed.) Neuroscience in Medicine. The Humana Press, Totowa, NJ., pp. 403-417.

182. Smith, Y. (2005) Glutamatergic pathways: Their relevance for Psychiatric Diseases. IN WJ Schmidt and MEA Reith (eds). Dopamine and Glutamate in Psychiatric Disorders. Humana Press: Totowa, NJ., pp. 65-77.

183. Wichmann, T and Y Smith (2008) Functional Anatomy and Physiology of the Basal Ganglia: Motor Functions. In Deep Brain Stimulationin Neurological and Psychiatric Disorders (D. Tarsy, M. Okun, P. Starr and JL Vitek, eds). Humana Press: New Jersey.

184. Wichmann, T,  Smith, Y and Vitek, JL (2008) Basal Ganglia: Anatomy and Physiology. In Parkinson’s Disease: Diagnosis and Clinical Management (SA Factor and WJ Weiner, eds). Demos: New York.

185. Smith, Y. and D.V. Raju (2008) The Thalamus. In (P.M. Conn, ed.) Neuroscience in Medicine, 2nd edition. The Humana Press, Totowa, NJ.

186. Galvan, A and Y Smith (2009) Basal Ganglia. In: The Encyclopedia of Movement Disorders (MOVE). Elsevier: Oxford, UK (in press).

187. Bogenpohl, JW and Y Smith (2009) Direct Pathway.  In: The Encyclopedia of Movement Disorders (MOVE). Elsevier: Oxford, UK (in press).

188. Bogenpohl, JW and Y Smith (2009) Indirect Pathway. In: The Encyclopedia of Movement Disorders (MOVE). Elsevier: Oxford, UK (in press).

189. Smith , Y and JG Masilamoni (2009) The Substantia Nigra. In: The Encyclopedia of Movement Disorders (MOVE). Elsevier: Oxford, UK (in press).

190. Smith, Y (2009) Functional Anatomy of the Motor and Non-motor Circuitry of the Basal Ganglia. In: The non-motor and non-dopaminergic features of Parkinson’s disease, Olanow, Stocchi and Lang (eds). Blackwell Publishing Ltd: Oxford, UK (in press).

191. Smith, Y, A. Galvan, D. Raju and T. Wichmann (2009) Anatomical and functional organization of the thalamostriatal systems. In: Handbook of basal ganglia structure and function: A decade of progress; Steiner and Tseng (eds). Elsevier: New York (in press).

192. Smith Y (2009) Functional Anatomy of the Basal Ganglia. In Movement Disorders, 3rd edition; Watts, Obeso and Standaert (eds).  McGraw Hill: New York (in press).

193. Smith Y (2009) Anatomy and synaptic connectivity of the basal ganglia. In Youman’s Neurological Surgery: Expert Consult-online and Print: 4 volume set, 6th edition; Winn (ed.). Elsevier: The Netherlands (in press).

 

(E) SELECTED ABSTRACTS: 201

1. Parent, A., L. De Bellefeuille, Y. Smith and A. Mackey (1983) The output organization of the pallidum and substantia nigra in primate. Proceedings of the satellite symposium (The Basal Ganglia - Structure and Function) of the XXIXth Int. Congress of the I.U.P.S., Sept. 5-7, p. 40.

2. Smith, Y., A. Mackey, L. De Bellefeuille and A. Parent (1983) The output organization of the substantia nigra pars reticulata in the primate. Soc. for Neurosci., 9:662.

3. Parent, A., C. Bouchard, Y. Smith and R. Boucher (1984) The organization of the striatofugal fiber system in primate. Anat. Rec., 208:133A.

4. Parent, A., Y. Smith and C. Bouchard (1984) Differential connections of caudate nucleus and putamen in monkey. Soc. for Neurosci., 10:179.

5. Smith, Y., L. Kerkérian, G. Pelletier and A. Parent (1984) Immunohistochemical localization of neuropeptide Y in basal forebrain and upper brainstem of monkey. Soc. for Neurosci., 10:430.

6. Smith, Y. and A. Parent (1984) Etude des projections efférentes de la substance noire pars reticulata (SNr) chez le primate. Annales de l'ACFAS, 51:200.

7. Smith, Y., J. Dumas and A. Parent (1985) Neuropeptide Y in striatum: A morphological, hodological and co-localization study. XXème Congrès des Sciences Neurol. J. Can. Sci. Neurol., 12:180.

8. Smith, Y. and A. Parent (1985) Characterization of Neuropeptide Y-immunoreactive neurons in striatum of cats and monkeys. Soc. for Neurosci., 11:207.

9. Paré, D., M. Steriade, Y. Smith and A. Parent (1986) Thalamic targets of brainstem cholinergic neurons in the cat. Soc. for Neurosci., 12:355.

10. Parent, A. and Y. Smith (1986) GABA-immunoreactive neurons in primate basal ganglia. Proceedings of the XXXth Int. Congress of the I.U.P.S., 16:518.

11. Parent, A. and Y. Smith (1986) Double-labeling study of efferent connections of subthalamic nucleus in the squirrel monkey. Soc. for Neurosci., 12:1542.

12. Parent, A., Y. Smith and M.-Y. Arsenault (1986) Immunohistochemical localization of neurotransmitters in primate basal ganglia. Proceedings of the satellite symposium (The Basal Ganglia - Structure and Function II) of the XXXth Int. Congress of the I.U.P.S., July 21-23, p. 3.

13. Smith, Y., A. Parent, P. Séguéla and L. Descarries (1986) Immunohistochemical localization of GABA-immunoreactive neurons in the basal ganglia of the squirrel monkey. Soc. for Neurosci., 12:874.

14. Parent, A. and Y. Smith (1987) A model of primate subthalamic nucleus based on analysis of its efferent projections. Anat. Rec., 218: 103A.

15. Parent, A. and Y. Smith (1987) A new model of the organization of the subthalamic nucleus in primates. Neurosci. Suppl., 22:S295.

16. Hazrati, L., A. Parent and Y. Smith (1987) Organization of striatal and subthalamic afferents to pallidum in primate as revealed by PHA-L anterograde tracing method. Soc. for Neurosci., 13:1571.

17. Parent, A., Y. Smith, D. Paré and M. Steriade (1987) Basal forebrain cholinergic and non-cholinergic projections to the thalamus and brainstem in cats and monkeys. Soc. for Neurosci., 13:445.

18. Smith, Y. and A. Parent (1987) Dopaminergic innervation of pallidum and subthalamic nucleus in primate. Soc. for Neurosci., 13:1571.

19. Boegman, R.J., Y. Smith, A. Parent, J.-C. Martel and R. Quirion (1988) Differential regulation of striatal neuropeptide Y and somatostatin containing neurons in the rat. Soc. for Neurosci., 14:92

20. Hazrati, L.-N., Y. Smith and A. Parent (1988) Organization of efferent projections of the subthalamic nucleus in primates. XXIIIème Congrès des Sciences Neurol., J. Can. Sci. Neurol., 15:219.

21. Lavoie, B., Y. Smith and A. Parent (1988) Dopaminergic innervation of the pallidum and subthalamic nucleus in primates: a tyrosine hydroxylase immunohistochemical study. XXIII ème Congrès des Sciences Neurol., J. Can. Sci. Neurol., 15:215.

22. Lavoie, B., Y. Smith and A. Parent (1988) Distribution of serotonin immunoreactivity in primate basal ganglia. Soc. for Neurosci., 14:719.

23. Parent, A. and Y. Smith (1988) The organization of the subthalamic nucleus in primates: a study of efferent projections and transmitter localization. Proceed. Intern. Conf. on Neural Mechanisms in Disorders of Movement. Manchester April 12-14, p.23.

24. Parent, A., Y. Smith and B. Lavoie (1988) Dopaminergic innervation of the pallidum and subthalamic nucleus in primates as revealed by tyrosine hydroxylase (TH) immunohistochemistry. Proceed. 9th International Symposium on Parkinson's Disease. Jerusalem, June 5-9, p.8.

25. Sadikot, A.F., Y. Smith and A. Parent (1988) Chemical anatomy of the amygdala in primate. Soc. for Neurosci., 14:860.

26. Smith, Y., A. Parent and J. Dumas (1988) Organization of efferent connections of the two pallidal segments in primate as revealed by PHA-L anterograde tracing method. Soc. for Neurosci., 14:719.

27. Bolam, J.P. and Y. Smith (1989) Characterization of the synaptic inputs to the dopaminergic neurons in the rat substantia nigra. Proceed. of the IIIrd triennal International Basal Ganglia Society meeting, Cagliari, June 10-13, p. 20.

28. Parent, A., B. Lavoie, L.-N. Hazrati and Y. Smith (1989) Differential connections of the two pallidal segments in the squirrel monkey. Proceed. of the IIIrd triennal International Basal Ganglia Society meeting, Cagliari, June 10-13, p. 130.

29. Smith, Y. and J.P. Bolam (1989) Anatomical and immunohistochemical evidence that the output cells in the rat substantia nigra receive a strong GABA input from the globus pallidus. Proceed. of the IIIrd triennal International Basal Ganglia Society meeting, Cagliari, June 10-13, p. 164.

30. Smith, Y. and J.P. Bolam (1990) Anatomical and immunohistochemical study of the topography, synaptic organization and neurotransmitter content of the pallidosubthalamic projection in the rat. Neurosci. Lett., Suppl. 38: S93.

31. Smith, Y. and J.P. Bolam (1990) Convergence of pallidal and striatal inputs to neurones in the entopeduncular nucleus and substantia nigra if the rat: application of a new double anterograde labeling method at electron microscopic level. Soc. for Neurosci. 16: 236.

32. Bolam, J.P. and Y. Smith (1991) Convergence of terminals from the striatum and the globus pallidus onto neurones in the substantia nigra and the entopeduncular nucleus. Satellite symposium of European Neuroscience Association Meeting: "Chemical signalling in the basal ganglia". Sept. 7-8, Babraham, Cambridge, U.K.

33. Lapper, S.R., Y. Smith, A.F. Sadikot, A. Parent and J.P. Bolam (1991) Cortical input to parvalbumin-immunoreactive neurons in the striatum of the monkey. IBRO Proceedings, p. 143.

34. Sadikot, A.F., A. Parent, Y. Smith and J.P. Bolam (1991) Relationship between the centromedian-parafascicular thalamic complex and the basal ganglia in primates. IBRO Proceedings, p. 144.

35. Smith, Y. and J.P. Bolam (1991) Convergence of terminals from the striatum and the globus pallidus onto single neurones in the entopeduncular nucleus of the rat. IBRO Proceedings, p. 144.

36. von Krosigk, M., Y. Smith, J.P. Bolam and A.D. Smith (1991) Convergence of synaptic inputs from restricted regions of the striatum and the globus pallidus onto single nigroreticular neurons in the rat. IBRO Proceedings, p. 144.

37. Bolam, J.P., B. Bennett, S.R. Lapper, A.D. Smith and Y. Smith (1992) The internal organisation of the neostriatum at the synaptic level: some speculations concerning the striosome/patch matrix system. IV th IBAGS Meeting, Oct. 6 th-9 th, Giens, France.

38. Smith, Y., T. Wichmann and M.R. DeLong (1992) Synaptic innervation of the globus pallidus by the subthalamic nucleus in monkey. IV th IBAGS Meeting, Oct. 6 th-9 th, Giens, France.

39. Smith, Y. (1993) A direct projection from the external to the internal segments of the globus pallidus: Anatomical and functional significance. Brain Res. Assoc. Abstr., 10: 50.

40. Smith, Y., B.D. Bennett, J.P. Bolam, A. Parent and A.F. Sadikot (1993) Synaptic interactions between the dopaminergic afferents and the cortical or thalamic input at the single cell level in the striatum of monkey. Soc. for Neurosci. 19: 977.

41. Bolam, J.P., B.D. Bennett, Y. Smith, Z.-P. Mi, and M. Palmi (1993) Synaptic connections of corticostriatal fibres in relation to striatal circuits. Int. symposium; 50th Anniversary Osaka Univ., Dec. 13-15.

42. Bolam, J.P., Y. Smith, B.D. Bennett, A. Parent and A.F. Sadikot (1993) Convergence of thalamic and cortical inputs in the sensorimotor sector of the striatum in monkey. Soc. for Neurosci. 19: 977.

43. Charara, A., Y. Smith and A. Parent (1993) Glutamatergic inputs from the pedunculopontine nucleus to the midbrain dopaminergic neurons in primates: A light and electron microscopic study. Soc. for Neurosci. 19: 1437.

44. Paré, D., Y. Smith and J.-F. Paré (1993) GABAergic projections from the intercalated cell masses (ICMs) to the centromedial (CM) amygdaloid complex and basal forebrain (BF). Soc. for Neurosci. 19: 1440.

45. Charara, A., Y. Smith et A. Parent (1994) Organisation synaptique des projections glutamatergiques du noyau pédonculopontin vers les neurones dopaminergiques du mésencéphale chez le primate. Ann. de l'ACFAS, 238.

46. Shink, E. et Y. Smith (1994) Organisation synaptique des afférences GABAergiques et glutamatergiques aux neurones du pallidum chez le singe-écureuil. Ann. de l'ACFAS, 242.

47. Sidibé, M. et Y. Smith (1994) Organisation synaptique des afférences thalamiques sur les neurones de projection du striatum chez le singe. Ann. de l'ACFAS, 242.

48. Moukhles, H., Y. Smith, P. Pierret and G. Doucet (1994) Host projections into intrastriatal transplants: Demonstration of afferents from the globus pallidus but not from the thalamus. Soc. for Neurosci., 20: 471.

49. Shink, E. and Y. Smith (1994) Differential synaptic innervation of neurones in the external and the internal pallidum in monkey. Soc. for Neurosci., 20: 332.

50. Sidibé, M. and Y. Smith (1994) Differential synaptic innervation of striatal neurones projecting to the internal or the external segments of the globus pallidus by thalamic afferents in monkeys. Soc. for Neurosci., 20: 783.

51. Smith, Y., A. Charara and A. Parent (1994) Differential synaptic innervation of dopaminergic neurones in the ventral tegmental area and the substantia nigra pars compacta by glutamate-containing terminals in squirrel monkeys. Mov. Disorders, 9 (suppl. 1): P453.

52. Smith, Y., M. Sidibé and E. Shink (1994) A light and electron microscopic analysis of the interconnections between the two pallidal segments and the subthalamic nucleus in the squirrel monkey. Soc. for Neurosci., 20: 332

53. Paquet, M. and Y. Smith (1995) Localisation des récepteurs à glutamate au niveau des neurones dopaminergiques dyu mésencéphale chez le singe. Ann. de l'ACFAS, p. 225.

54. Shink, E. and Y. Smith (1995) Analyse des interconnexions entre les deux segments du globus pallidus et le noyau sousthalamique chez le singe-écureuil. Ann. de l'ACFAS, p. 226.

55. Shink, E. and Y. Smith (1995) The GABA- and glutamate-enriched terminals are distributed differently on neurones in the internal or the external segments of the globus pallidus in primates. Brain Res. Ass. Abstr. 12: 38

56. Sidibé, M. and Y. Smith (1995) Organisation de la voie pallidothalamique chez le singe-écureuil. Ann. de l'ACFAS, p. 226.

57. Sidibé, M. and Y. Smith (1995) Differential synaptic interaction between thalamic afferents and striatopallidal neurones innervating the internal or the external segments of the globus pallidus in primates. Brain Res. Ass. Abstr. 12: 38

58. Smith, Y., E. Shink, M.D. Bevan and J.P. Bolam (1995) The subthalamic nucleus and the external pallidum: Two tightly interconnected structures that control the output of the basal ganglia in primates. Brain Res. Ass. Abstr. 12: 89.

59. Smith, Y., A. Charara, M. Paquet and A. Parent (1995) Synaptic relationships between glutamate-enriched terminals and midbrain dopaminergic neurones in monkeys. Brain Res. Ass. Abstr. 12: 38

60. Rudkin, T., A. Sadikot, Y. Smith and A.J. Morin (1995) Synaptic interactions between amygdalo-striatal afferents and parvalbumin and calretinin interneurons within the rat ventral striatum. Soc. for Neurosci. 21: 1665.

61. Paré, D., Y. Smith and J.-F. Paré (1995) Intrathalamic projections of the intralaminar nuclei (ITN): Possible anatomical substrate of large-scale thalamocortical synchronization. Soc. for Neurosci. 21: 112.

62. Paquet, M., J.-J. Soghomonian and Y. Smith (1995) Cellular and sub-cellular localization of glutamate receptors in midbrain dopaminergic neurones in the squirrel monkey. Soc. for Neurosci. 21: 348.

63. Shink, E. and Y. Smith (1995) Synaptic organization of GABAergic terminals in the subthalamic nucleus (STN) of the squirrel monkey. Soc. for Neurosci. 21: 676.

64. Sidibé, M., M.D. Bevan, J.P. Bolam and Y. Smith (1995) Functional segregation and synaptic organization of the pallidothalamic projection in primates. Soc. for Neurosci. 21: 676.

65. Smith, Y. and E. Shink (1995) The pedunculopontine nucleus (PPN): A potential target for the convergence of informations arising from differential functional territories of the internal pallidum (GPi) in primates. Soc. for Neurosci. 21: 677.

66. Sadikot, A.F., T. Rudkin and Y. Smith (1995) Sources of interaction between the limbic system and the basal ganglia: Interneuron targets for the amygdalostriatal projection. Proc. of the Vth IBAGS meeting; Nemuno-Sato, Japan.

67. Sidibé, M. and Y. Smith (1996) Analyse des interactions synaptiques entre les afférences thalamiques et les interneurones au niveau du striatum chez le singe-écureuil (Saimiri sciureus). 64e Congrès de l'ACFAS, Univ. McGill, Montréal.

68. Shink, E. and Y. Smith (1996) Le noyau pédonculopontin: une zone d'intégration des informations provenant de différents territoires fonctionnels du globus pallidus interne (GPi) chez le primate. 64e Congrès de l'ACFAS, Univ. McGill, Montréal.

69. Sidibé, M. and Y. Smith (1996) Synaptic interactions between thalamic afferents and striatal interneurones in monkeys. Soc. for Neurosci. 22: 411.

70. Smith, Y., M. Paquet and J.-F. Bouffard (1996) Localization of metabotropic glutamate receptor subunits in the basal ganglia of monkeys. Soc. for Neurosci. 22: 411.

71. Shink, E., M. Sidibé, J.-F. Bouffard and Y. Smith (1996) Efferent projections of different functional territories of the internal pallidum in monkeys. Soc. for Neurosci. 22: 411.

72. Pinault, D., Y. Smith and M. Deschênes (1996) Combined light and electron microscopic evidence for the lack of intrinsic axon collaterals and the existence of dendro-dendritic synapses in the thalamic reticular nucleus of the rat. Soc. for Neurosci. 22: 2030.

73. Paquet, M. and Y. Smith (1996) Localization of AMPA and NMDA receptor subunits in striatal interneurones in monkeys. Soc. for Neurosci. 22: 411.

74. Paré, J.-F., Y. Smith and D. Paré (1996) Synaptic organization of parvalbumin-immunoreactive neurones in the lateral and basolateral amygdaloid nuclei in the cat. Soc. for Neurosci. 22: 2049.

75. Clarke, N.P., Y. Smith and J.P. Bolam (1997) Cholinergic neurons in the centromedian/parafascicular thalamic nucleus of the rat and squirrel monkey. Brain Res. Ass. Abstr. 14:

76. Smith, Y., M. Paquet, A. Charara, A. Parent and J.-J. Soghomonian (1997) Glutamate inputs to midbrain dopaminergic neurones in primates: Synaptic relationships and localization of glutamate receptor subunits. XIIth International Symposium on Parkinson's Disease, London, UK. Mov. Disorders 12: 139.

77. Paré, J.-F., Y. Smith, D. Paré and M. Filion (1997) Cortical inputs to inhibitory interneurons of the basolateral (BL) amygdaloid complex. Soc. for Neurosci. 23: 2102.

78. Freedman, L., J.-F. Paré, T.R. Insel and Y. Smith (1997) Subcortical projections of macaque infralimbic cortex (area 25). Soc. for Neurosci. 23: 901.

79. Hooda, R., M. Paquet and Y. Smith and M. Tigges (1997) Coexistence of glutamate receptors in cholinergic neurones of the basal forebrain in monkeys. Soc. for Neurosci. 23: 1894.

80. Paquet, M. and Y. Smith (1997) Differential distribution of metabotropic glutamate receptors (mGluRs) in the monkey striatum. Soc. for Neurosci. 23: 188.

81. Smith, Y., J.-F. Paré, E. Koylu, P. Couceyro, E. Ince, A.I. Levey and M.H. Kuhar (1997) CART peptide immunoreactivity in the nucleus accumbens of monkeys: Electron microscopic analysis and co-localization studies. Soc. for Neurosci. 23: 966.

82. Sidibé, M., M. Paquet, A.I. Levey and Y. Smith (1997) NMDAR1 subunit immunoreactivity in pre-synaptic terminals: Electron microscopic characterization and species difference between rats and monkeys. Soc. for Neurosci. 23: 1752.

83. Baron, M.S., E. Shink, M. Sidibé, C. Mewes, J.L. Vitek, Y. Smith and M.R. DeLong (1997) Functional delineation of the course of the ansa lenticularis and the lenticular fasciculus based on GPi efferents in primates. Soc. for Neurosci. 23: 197.

84. Thomas, T.M., J.-F. Paré, Y. Smith and S. Hersch (1997) Analysis of frontal cortical inputs to striatal cholinergic interneurons in monkey. Soc. for Neurosci. 23: 194.

85. Smith, Y., E. Koylu, P. Couceyro and M.J. Kuhar (1997) Electron microscopic localization of CART peptide immunoreactivity in the nucleus accumbens of monkeys. CPDD Abstract, Nashville, TN.

86. Baron, M.S., M.A. Demin, E. Shink, M. Sidibé, K. Mewes, J.L. Vitek, M.R. DeLong and Y. Smith (1998) A novel targeting scheme for performing GPi pallidotomy derived from the functional delineation of pallidal projections in primates. AAAN (in press).

87. Dall Vechia, S.E., J.-F. Paré, P. Lambert, P. Couceyro, M. Kuhar and Y. Smith (1998) CART peptide immunoreactivity in the hypothalamic PVN in monkeys: Distribution and interactions with NPY. CPDD abstr. (in press).

88. Alagarsamy, S., S.T. Rouse, R.W. Gereau, S.F. Heinemann, Y. Smith and P.J. Conn (1998) NMDA-induced reversal of mGluR5 desensitization.

89. Paré, J.-F., S.E. Dall Vechia, P. Lambert, P. Couceyro, B.E. Garrett, M. Kuhar and Y. Smith (1998) CART peptide-immunoreactive neurons in the monkey PVN: Electron microscopic characterization and synaptic relationships with NPY-immunoreactive terminals. Soc. for Neurosci. 24: 2043.

90. Dall Vechia, S.E., J.-F. Paré, P. Lambert, P. Couceyro, M. Kuhar and Y. Smith (1998) Synaptic interactions between CART peptide-immunoreactive terminals and midbrain dopaminergic neurons in the rat. Soc. for Neurosci. 24: 2043.

91. Smith, Y., A. Charara, J.D. Rothstein and L.J. Freedman (1998) Glutamate transporters in the striatopallidal complex and the subthalamic nucleus (STN) in monkeys. Soc. for Neurosci. 24: 2068.

92. Charara, A. and Y. Smith (1998) Subsynaptic distribution of GABA-A receptor subunits in the globus pallidus and subthalamic nucleus in monkeys. Soc. for Neurosci. 24: 1650.

93. Paquet, M., M. Donnelly, J.D. Rothstein and Y. Smith (1998) Glutamate transporters in midbrain dopaminergic (DA) structures in monkeys. Soc. for Neurosci. 24: 2068.

94. Hubert, G.W., J.-F. Paré, A.M. Robida, S.R. Bradley, A.I. Levey, P.J. Conn and Y. Smith (1998) Subsynaptic localization of metabotropic glutamate receptors (mGluRs) in the globus pallidus and subthalamic nucleus in monkeys. Soc. for Neurosci. 24: 1650.

95. Charara A., J.D. Rothstein and Y. Smith (1998) Electron microscopic localization of glutamate transporters in the basal ganglia in monkeys: I. Caudate nucleus and putamen. Proceedings 6th International Basal Ganglia Society Meeting, Brewster, MA, p. 60.

96. Charara, A., J.D. Rothstein and Y. Smith (1998) Electron microscopic localization of glutamate transporters in the basal ganglia in monkeys: II. Globus pallidus and subthalamic nucleus (STH). Proceedings 6th International Basal Ganglia Society Meeting, Brewster, MA, p. 61.

97. Paquet, M., M. Donnely, J.D. Rothstein and Y. Smith (1998) Electron microscopic localization of glutamate transporters in the basal ganglia in monkeys: III. Midbrain dopaminergic cell groups. Proceedings 6th International Basal Ganglia Society Meeting, Brewster, MA, p. 66.

98. Charara, A. and Y. Smith (1998) Subsynaptic distribution of GABA-A receptor subunits in the globus pallidus (GP) and subthalamic nucleus (STH) in monkeys. Proceedings 6th International Basal Ganglia Society Meeting, Brewster, MA (in press), p. 60.

99. Kieval, J.Z., J.-F. Paré, P. Couceyro, M.J. Kuhar and Y. Smith (1998) Electron microscopic characterization of CART peptide-immunoreactive neurones in the nucleus accumbens in monkeys. Proceedings 6th International Basal Ganglia Society Meeting, Brewster, MA, p. 62.

100. Dall Vechia, S.E., J.-F. Paré, P. Lambert, P. Couceyro, M.J. Kuhar and Y. Smith (1998) Electron microscopic characterization of CART peptide-immunoreactive terminals in the substantia nigra compacta in rats. Proceedings 6th International Basal Ganglia Society Meeting, Brewster, MA, p. 62.

101. Smith, Y., G.W. Hubert, J.E. Hanson, J.-F. Paré, S.R. Bradley, P.J. Conn and A.I. Levey (1998) Subsynaptic localization of metabotropic glutamate receptors in the basal ganglia in monkeys: II. Globus pallidus and subthalamic nucleus. Proceedings 6th International Basal Ganglia Society Meeting, Brewster, MA, p. 12

102. Paquet, M., S.R. Bradley, P.J. Conn, A.I. Levey and Y. Smith (1998) Subsynaptic localization of metabotropic glutamate receptors in the basal ganglia in monkeys: I. Striatum. Proceedings 6th International Basal Ganglia Society Meeting, Brewster, MA, p. 67.

103. Paquet, M., J.-F. Paré, S.R. Bradley, A.I. Levey, P.J. Conn and Y. Smith (1998) Subsynaptic localization of metabotropic glutamate receptors in the basal ganglia in monkeys: III. Midbrain dopaminergic cell groups. Proceedings 6th International Basal Ganglia Society Meeting, Brewster, MA, p. 67.

104. Paquet, M. and Y. Smith (1998) Pre-synaptic NMDA receptors in GABAergic terminals: Ultrastructural evidence and species difference between rats and monkeys. Proc. of Symposium: Glutamate Cascade: Common Pathways of Central Nervous System Disease States, May 03-05, NIH, Bethesda, MD, USA, p. 73.

105. Smith, Y ., J.E. Hanson, A. Charara and A.I. Levey (1999) New ideas on receptor localization in the basal ganglia. Proceedings Anatomical Society Symposium, Glasgow.

106. Smith, Y . and M. Sidibé (1999) Functional interconnections between the caudal intralaminar nuclei and the striatopallidal complex in monkeys. Soc. For Neurosci. 25: 884.19.

107. Hubert, G.W. and Y. Smith (1999) Subsynaptic localization of group I metabotropic glutamate receptors (mGluRs) in the ventral midbrain of rats. Soc. For Neurosci. 25: 468.10.

108. Paquet, M., S.R. Bradley, J. Conn and Y. Smith (1999) Subcellular and subsynaptic distribution of metabotropic glutamate receptors in the monkey striatum. Soc. For Neurosci. 25: 176.9.

109. Charara, A., C. Heilman, A.I. Levey and Y. Smith (1999) Cellular and subcellular localization of GABAB receptors in the basal ganglia in monkeys. Soc. For Neurosci. 25: 468.9.

110. Dall Vechia, S., W. Gong, Y. Smith and M.J. Kuhar (1999) Selective excitotoxic lesions of the nucleus accumbens in rats: Differential effects of CART peptide-IR varicosities in the ventral midbrain. Soc. For Neurosci. 25: 884.19.

111. Paré, J.-F ., A. Charara and Y. Smith (1999) High pressure freezing and freeze substitution as tools for post-embedding immunocytochemistry in monkey brain sections. Microsc. Microanal., Vol. 5: 1300.

112. Dall Vechia, S., Y. Smith, W. Gong and M. Kuhar (2000) Excitotoxic lesions of nucleus accumbens in rats: Effect on CARTir varicosities in the midbrain. CPDD Abstr.

113. Adams , S.D., M.J. Kuhar and Y. Smith (2000) CART peptides’ role in psychomotor stimulant-like behavioral effects: Anatomical substrates. Soc. For Neurosci. 26: 18.3.

114. Muly, E.C., Y. Smith, P. Greengard and P.S. Goldman-Rakic (2000) The relationships between local horizontal afferents and dendritic spines containing different isoforms of protein phosphatase-1 in primate prefrontal cortex. Soc. For Neurosci. 26: 49.23.

115. Hanson, J.E. and Y. Smith (2000) Subcellular localization of calcium and sodium channel subtypes in the rat globus pallidus. Soc. For Neurosci. 26: 135.16.

116. Sanchez, M.M., A. Charara, J.-F. Paré, Y. Smith and P.M. Plotsky (2000) Pre- and post-synaptic localization of glucocorticoid receptors in the primate hippocampal formation. Soc. For Neurosci. 26: 152.5.

117. Martina, M., S. Royer, J.-F. Paré, Y. Smith and D. Paré (2000) Perirhinal propagation of neocortical inputs. Soc. for Neurosci. 26: 172.14.

118. Hubert, G.W., C.J. Heilman, A.I. Levey and Y. Smith (2000) Development of an antibody for immunohistochemical detection of the metabotropic glutamate receptor 1D in the CNS. Soc. For Neurosci. 26: 341.12.

119. Smith , Y ., M. Sidibé and J.-F. Paré (2000) Synaptic inputs from the substantia nigra and the pedunculopontine nucleus to thalamostriatal neurons. Soc. for Neurosci. 26: 361.15.

120. Charara, A., A. Kulik, R. Shigemoto and Y. Smith (2000) Cellular and subcellular localization of GABA-BR2 recepotrs in the basal ganglia. Soc. for Neurosci. 26: 740.12.

121. Paquet, M. and Y. Smith (2000) Subsynaptic localization of group I metabotropic glutamate receptors at glutamatergic synapses in the monkey striatum. Soc. for Neurosci. 26: 740.13.

122. Marino, M.J., G.W. Hubert, Y. Smith and P.J. Conn (2000) Functional roles of group I metabotropic glutamate in the substantai nigra pars reticulata. Soc. for Neurosci. 26: 740.16.

123. Kieval, J.Z., A. Charara, J.-F. Paré and Y. Smith (2000) Subcellular localization of kainate receptors in the monkey striatum. Soc. for Neurosci. 26: 741.15.

124. Smith, Y., J.Z. Kieval and A. Charara (2001) Pre- and post-synaptic kainate receptors in the striatum. Proceedings 11 th Neuropharmacology Conference, Abstr. 2.06.

125. Soares, J., A. Galvan, T. Wichmann, N.T. Maidment, A. Charara, M.A. Kliem and Y. Smith (2001) Effects of GABA-B receptor activation on glutamate and GABA release in the globus pallidus and subthalamic nucleus of monkey. Soc. for Neurosci. 27: 826.11.

126. Galvan, A., A. Charara, J.-F. Pare, A.I. Levey, J.-M. Fritschy and Y. Smith (2001) Differential subcellular and subsynaptic distribution of GABA-B and GABA-A receptors in the subthalamic nucleus. Soc. for Neurosci. 27: 290.10.

127. Weeks, J.L., Kane-Jackson, R. and Y. Smith (2001) Kainate receptors in the primate striatum: Relationships with direct and indirect striatofugal neurons. Soc. for Neurosci. 27: 291.9.

128. Hanson, J.E., D. Jaeger and Y. Smith (2001) Subcellular localization of sodium channels in the rat globus pallidus and dendritic boosting of synaptic inputs. Soc. for Neurosci. 27: 502.3.

129. Dall Vechia Adams, S., M.J. Kuhar and Y. Smith (2001) CART peptide immunoreactive terminals in the ventral midbrain: Synaptic connectivity with dopaminergic neurons and neurochemical characterization. Soc. for Neurosci. 27: 239.8.

130. Kuwajima, M., K.B. Philpot, J.-F. Pare and Y. Smith (2001) Subcellular localization of group I metabotropic glutamate receptors in the monkey subthalamic nucleus. Soc. for Neurosci. 27: 290.12.

131. Hubert, G.W. and Y. Smith (2001) Developmental differences in the expression of group I metabotropic glutamate receptors (mGluRs) in the substantia nigra (SN) of the rat. Soc. for Neurosci. 27: 913.6.

132. Sidibe, M., J.-F. Pare and Y. Smith (2001) Co-localization of GABA and choline acetyltransferase in pedunculopontine projections to the centre median/parafascicular (CM/PF) nuclei in monkeys. Soc. for Neurosci. 27: 290.15.

133. Smith, Y., J.-F. Pare and A. Charara (2001) Subsynaptic localization of GABA-A and GABA-B receptors in the monkey globus pallidus. Soc. for Neurosci. 27: 290.11.

134. Mazloom, M. and Y. Smith (2001) Ultrastructural characterization of intrastriatal dopaminergic neurons in MPTP-treated monkeys. Soc. For Neurosci. 27: 292.9.

135. Muly, E.C., Y. Smith and P. Greengard (2001) Localization of spinophilin within spines in primate prefrontal cortex (PFC) using post-embedding immunogold labeling. Soc. For Neurosci. 27: 269.6.

136. Poisik, O., Y. Smith and P.J. Conn (2001) Group I metabotropic glutamate receptors 1 and 5 have distinct functional roles in rat globus pallidus. Soc. For Neurosci. 27: 291.15.

137. Smith, Y., M. Sidibe and J.-F. Pare and D. Raju (2001) Anatomical and functional relationships between intralaminar thalamic nuclei and basal ganglia in monkeys. Proc. VIIth IBAGS meeting, New Zealand.

138. Ciombor, K.J., P.J. Conn and Y. Smith (2002) Group I metabotropic glutamate receptor (mGluR) pharmacology in dopaminergic neurons of the ventral tegmental area and the substantia nigra pars compacta in rats. 3 rd International MGlur Meeting, Taormina, Sicily, Italy. Neuropharmacology 43: 281.

139. Hubert, G.W. and Y. Smith (2002) Group I metabotropic glutamate receptors (mGluRs) localization in the substantia nigra of rats. 3 rd International MGlur Meeting, Taormina, Sicily, Italy. Neuropharmacology 43: 289.

140. Kuwajima, M., G.W. Hubert and Y. Smith (2002) Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the subthalamic nucleus of normal animals and animal models of Parkinson’s disease. 3 rd International MGlur Meeting, Taormina, Sicily, Italy. Neuropharmacology 43: 293.

141. Poisik, O., G. Mannaionin, S. Traynelis, Y. Smith and P.J. Conn (2002) Distinct functions of group I metabotropic glutamate receptors 1 and 5 in the rat globus pallidus. 3 rd International MGlur Meeting, Taormina, Sicily, Italy. Neuropharmacology 43: 305.

142. Smith, Y., G.W. Hubert, M. Paquet, M. Kuwajima and J.E. Hanson (2002) Differential subcellular distribution of mGluR1a and mGluR5 in the primate basal ganglia. 3 rd International MGlur Meeting, Taormina, Sicily, Italy. Neuropharmacology 43: 309.

143. Iskhakova, L.A., M. Paquet, J.-F. Pare and Y. Smith (2002) Subcellular localization of group II metabotropic glutamate receptors in the monkey striatum. Soc. For NS meeting abstr 63.3.

144. Sidibe, M., J.-F. Pare and Y. Smith (2002) Subcellular and subsynaptic localization of GABA-A alpha 1 and GABA-BR1 receptors subunits in the ventral motor and centromedian/ parafascicular (CM/Pf) thalamic nuclei in monkeys. Soc for NS meeting abstr 460.11.

145. Felger, J., J.-F. Pare, Y. Smith, Plotsky, PM and M. Sanchez (2002) Localization of glococorticoid receptors to presynaptic elements containing both GABA and glutamate in the primate hippocampus. Soc for NS meeting abstr. 470.15.

146. Kane-Jackson, R. and Y. Smith (2002) Pre- and post-synaptic kainate receptors in the monkey globus pallidus. Soc for NS meeting abstr 359.16.

147. Maxson, S., C. Bergston, K. Ciombor and Y. Smith (2002) Subcellular localization of calcyon in the striatum and subthalamic nucleus of normal and parkinsonian monkeys. Soc for NS abstr 63.14

148. Smith, Y., Betarbet, R., Pare, J.-F. and Greenamyre JT (2002) Subcellular localization of GluR1 AMPA glutamate receptor subunit in the striatum of normal and parkinsonian monkeys. Soc for NS meeting abstr 788.3.

149. Pare, J.-F., R. Samson, Y. Smith and D. Pare (2002) Transverse processing modules in the lateral nucleus of the amygdala. Soc for ns meeting abstr 587.7.

150. Smith, Y., Kieval, J. and D. Pinault (2002) Anatomical and ultrastructural features of physiologically identified thalamocortical inputs into the rat reticular thalamic nucleus. Eur NS meeting Abstr 118.12.

151. Galvan, A., Y. Shimo, M. Kliem, A. Charara, Y. Smith and T. Wichman (2003) Effects of GABA-A and GABA-B receptors stimulation on neuronal activity in the monkey globus pallidus. Soc. For Neurosci. Abstr. 706.14.

152. Jin, XT and Y. Smith (2003) Ultrastructural localization and functions of kainite receptors in the rat globus pallidus. Soc for Neurosci. 705.7.

153. Poisik, O., P.J. Conn and Y. Smith (2003) Metabotropic glutamate receptors modulate excitatory synaptic transmission in the rat globus pallidus. Soc For Neurosci. 705.9.

154. Mitrano, D.A., J.F. Pare and Y. Smith (2003) Subcellular and subsynaptic localization of mGluR5 in the shell and core of the nucleus accumbens in rhesus monkey. Soc. For Neurosci. 800.3.

155. Raju, D.V. and Y. Smith (2003) Differential subcellular localization of vesicular glutamate transporters in the striatopallidal complex. Soc. for Neurosci. 917.1.

156. Borges, K., H. Irier, D. McDermott, W. Hubert, Y. Smith and R. Dingledine (2003) Region-speciofic astrocyte degeneration after pilocarpine-induced status epilepticus. Soc. for Neurosci. 378.16.

157. Bordelon, J.R., Y. Smith, P. Greengard and E.C. Muly (2003) Localization of protein phosphatase-1 (PP1) isoforms in primate prefrontal cortex. Soc. for Neurosci. 52.8.

158. Hall. R.A., M. Kuwajima and Y. Smith (2003) Cocaine-induced upregulation of Homer 1A protein in the rat dopaminergic systems: A time-course study. Soc. for Neurosci. 855.20.

159. Smith, Y ., D. Raju and K.J. Ciombor (2003) Subcellular localization of neuronal and glial glutamate transporters in the monkey striatopallidal complex. Soc. for Neurosci. 917.2.

160. Hubert, G.W. and Y. Smith (2003) Expression of group I metabotropic glutamate receptors (mGluRs) and Homer 1 proteins in the substantia nigra pars reticulata (SNr) of rats in an animal model of Parkinson’s disease. Soc. for Neurosci. 800.4.

161. Kuwajima, M., M.H. Dehoff, P.F. Woerley and Y. Smith (2003) Subsynaptic localization of group I metabotropic glutamate receptors in the subthalamic nucleus of normal an d Homer 2-deficient mice. Soc. For Neurosci. 917.10.

162. Pare, J.-F., M. Sidibe and Y. Smith (2003) Co-existence of GABA and acetylcholine in pedunculopontine tegmental inputs to caudal intralaminar nuclei, but not sensory relay nuclei in monkey thalamus. Soc. for Neurosci. 246.12.

163. Kuwajima, M, MH Dehoff, SC Collins, RA Hall, PF Woerley and Y Smith (2004) Homer proteins regulate the subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the mouse pallido-subthalamic complex . Society for NS, abstr. 162.4

164. Paquet, M, AM Castleberry, M Kuwajima, S Fam, CC Yun, Y Smith, RA Hall (2004) Metabotropic glutamate receptors interact with the scaffold protein NHERF-2. Society for NS abstr. 162.19.

165. Pare, J, Y Smith (2004) Acetylcholine co-localizes with GABA or glutamate in ascending brainstem inputs to the substantia nigra/ventral tegmental area and subthalamic nucleus in monkey. Soc for NS abstr 307.1

166. Raju, DV, J Pare and Y Smith (2004) A subset of cholinergic terminals co-express the vesicular glutamate transporter 1 in the monkey striatum. Soc for NS abstr 307.2

167. Mitrano, DA and Y Smith (2004) Localization of mGluR1a in the shell and core of the nucleus accumbens: A comparative analysis between monkeys and rats. Soc for NS abstr 393.4

168. Philpot, KB , S Dall Vechia Adams, Y Smith and MJ Kuhar (2004) The food connection: characterization of the synaptic connectivity of CART-immunoreactive neurons in the lateral hypothalamus/perifornical area in the rat. Soc for NS abstr 544.11

169. Bordelon, JR, Y Smith, LL Howell, P Greengard and EC Muly (2004) Differential localization of protein phosphatase-1 (PP1) isoforms at axospinous synapses: Response to haloperidol and cocaine treatment. Soc for NS abstr 632.8

170. Raju, DV and Y. Smith (2004) Differential subcellular distribution of vesicular glutamate transporters 1 and 2 in the rat striatum. 8 th IBAGS meeting, Crieff, P34.

171. Smith, Y and J-F Pare (2004) Differential co-localization of GABA and glutamate in ascending brainstem cholinergic inputs tobasal ganglia in monkeys. 8 th IBAGS meeting, Crieff, P45

172. Smith, Y , S. Haber, L. Kerkerian-LeGoff and I. Stanford (2004) The known, unknown and intriguing features of the thalamostriatal system. 8 th Ibags meeting, Crieff, S29.

173. Villalba, R and Y. Smith (2004) Comparative ultrastructural analysis of GABA-A and GABA-B receptors in basal ganglia-receiving thalamic nuclei in monkeys. 8 th IBAGS meeting, Crieff, P86.

174. Kuwajima, M., M. Dehoff, SC Collins, PF Woerley and Y. Smith (2004) Homer proteins regulate the subcellular localization of group I metabotropic glutamate receptors in the mouse globus pallidus: A comparative study with the subthalamic nucleus. 8 th IBAGS meeting, Crieff, P87.

175. Galvan, A., Y. Smith and T. Wichmann (2004) GABAergic transmission in the monkey globus pallidus: An in vivo study using extracellular recording and intracerebral drug infusion. 8 th IBAGS meeting, Crieff, P76.

176. Poisik, OV, A. Rodriguez, M. Verreault, PJ Conn and Y. Smith (2004) Metabotropic glutamate receptor 2 regulates excitatory synaptic transmission in the rat globus pallidus. 8 th IBAGS meeting, Crieff, P65.

177. Jin, XT, and Y. Smith (2004) Pre- and post-synaptic effects of kainate receptors on excitatory synaptic transmission in the rat globus pallidus. 8 th IBAGS meeting, Crieff, P 66.

178. Pare, J-F, DV Raju and Y. Smith (2005) Axonal tract tracing: A historical survey of neuroanatomical tract tracing methods. Soc for Neurosci abstr 18.19

179. Raju, DV, D. Lynn and Y. Smith (2005) Understanding neurological disease through neuroanatomy: A teaching module for first year undergraduate students. Soc for Neurosci. Abstr 20.9

180. Raju DV , DJ Shah, M Verreault, Y Smith (2005) Synaptology of thalamostriatal afferents from intralaminar and relay nuclei in rat. Soc for Neurosci. abstr 180.1

181. Pare J, DV Raju, TH Ahern and Y Smith (2005) Changes in subcellular distribution of vesicular glutamate transporter 1 in the MPTP monkey model of Parkinson’s disease. Soc for Neurosci abstr 180.2

182. Smith Y ., DV Raju, TH Ahern and M Verreault (2005) Striatal and cortical projections of the dorsal and ventral tier thalamic relay nuclei in rat. Soc for Neurosci abstr 180.9

183. Borges, K, H Irier, Y Smith and R Dingledine (2005) Degeneration and repopulation of astrocytes in dentate gyrus after pilocarpine-induced status epilepticus. Soc for Neurosci Abstr 217.14

184. Poisik, OV, PJ Conn and Y Smith (2005) Dopamine modulates the functions of the group I metabotropic glutamate receptors in the rat globus pallidus. Soc for Neurosci Abstr. 263.12

185. Kuwajima, M, RA Hall and Y Smith (2005) Expression of group I metabotropic glutamate receptors in the pallido-subthalamic complex in the MPTP-mouse model of Parkinson’s disease. Soc for Neurosci abstr 331.8

186. Jin, X and Y Smith (2005) Presynaptic kainate receptor modulates GABAergic and glutamatergic transmission in the rat globus pallidus. Soc for Neurosci Abstr 631.8

187. Villalba, RM and Y Smith (2005) Subsynaptic localization of GABA-B receptors at glutamatergic synapses in the monkey thalamus. Soc for Neurosci abstr 959.2

188. Mitrano DA and Y Smith (2005) Subsynaptic localization of group I mGluRs in the nucleus accumbens of normal and cocaine-treated rats. 5 th International mGluRs meeting, Taormina, abstr 85

189. Jones CK, MJ Marino, Y Nong, O Valenti, GG Kinney, O Poisik, L Williams, Y Smith and PJ Conn (2005) Modulation of the basal ganglia by metabotropic glutamate receptors: potential novel approaches for the treatment of Parkinson’s disease. 5 th International mGluRs meting, Taormina, abstr 65.

190. Poisik, OV, PJ Conn and Y Smith (2005) Modulation of group I metabotropic glutamate receptor function by D2-like dopamine receptors in the rat globus pallidus. 5 th International mGluR meeting, Taormina, abstr 113.

191. Smith Y , M Kuwajima, RA Hall, P Worley and M. Dehoff (2005) Homer regulation of group I metabotropic glutamate receptors trafficking in the basal ganglia. 5 th International mGluRs meeting, Taormina, abstr 137.

192.Bonsi P, Sciamanna G, Cuomo D, Mitrano DA, Smith Y, Pisani, A (2006) Functional and ultrastructural analysis of group I mGluRs in striatal fast-spiking interneurons. Soc for Neurosci Abstr 56.14.

193.Bogenpohl JW, Verreault M, Galvan A, Liu J, Smith Y (2006) The use of mGluR5 antagonists as antiparkinsonian therapy in MPTP-treated monkeys. Soc for Neurosci Abstr 175.3

194.Smith Y, Jin XT (2006) Blockade of GABA transporters (GAT-1 and GAT-3) modulates the glutamatergic and GABAergic transmission in the rat globus pallidus. Soc for Neurosci Abstr 254.1

195.Jin XT, Smith Y (2006) Presynaptic kainate receptor activation modulates GABAergic transmission in the rat globus pallidus. Soc for Neurosci Abstr 254.3

196.Mitrano DA, Arnold C, Smith Y (2006) Subcellular and subsynaptic localization of group I mGluRs in the nucleus accumbens following acute or chronic cocaine treatment in rats. Soc for Neurosci 331.4

197.Poisik OV, Conn PJ, Smith Y (2006) D1-like and D2-like dopamine receptors modulate the functions of group I mGluRs in the rat globus pallidus. Soc for Neurosci Abstr 331.15.

198.Tippens AL, Pare J, Smith Y, Lee A (2006) Postsynaptic localization of caldendrin, a neuronal Ca+2-binding protein, and Cav1.2 (L-type) Ca+2 channels in rat hippocampus. Soc for Neurosci abstr 340.4.

199.Galvan A, Smith Y, Wichmann T (2006) Modulation of the activity of globus pallidus neurons by GABA-A and GABA-B receptor ligands in an MPTP-treated monkey. Soc for Neurosci Abstr 380.12

200.Villalba RM, Verreault M, Smith Y (2006) Spine loss in the striatum of MPTP-treated monkeys. A correlation with the degree of striatal dopaminergic denervation. Soc for Neurosci Abstr 431.15

201.Kliem MA, Pare J, Maxson S, Wichmann T, Smith Y (2006) Comparative ultrastructural analysis of D1 and D5 dopamine receptor distribution in the substantia nigra and globus pallidus of normal and parknsonian monkeys. Soc for Neurosci Abstr 450.12.

202.Kliem, MA, Pare JF, Khan ZU, Wichmann T and Smith Y (2007) Comparative ultrastructural analysis of D1 and D5 dopoamine receptor distribution in the substantia nigra and globus pallidus of monkeys. IBAGS IXth Proceedings, Abstr P-018, p. 72.

203. Mitrano, D and Smith Y (2007) Differential glutamatergic innervation of mGluR1a- and mGluR5-containing neurons in the rat nucleus accumbens. IBAGS IXth Proceedings, Abstr P-024, p. 75.

204.Boghenpohl JW, Pare JF and Smith Y (2007) Subcellular localization of adenosine A2A receptors in the striatum and globus pallidus of monkey and rat. IBAGS IXth Proceedings, Abstr P-056, p. 93.

205.Galvan, A, Hu X, Smith Y and Wichmann T (2007) Changes in the subcellular localization and functions of GABA-B receptors in the globus pallidus of MPTP-treated monkeys. IBAGS IXth Proceedings, Abstr P-061, p. 95.

206.Jin XT and Smith Y (2007) Blockade of GABA transporter (GAT-1) modulates GABAergic transmission in the rat globus pallidus. IBAGS IXth Proceedings, Abstr P-094, p. 114.

207.Nanda, B, Galvan A, Smith Y and Wichmann T (2007) Effects of high frequency stimulation of the centromedian nucleus of thalamus on neuronal activity in the monkey striatum. IBAGS IXth Proceedings, Abstr P-129, p. 134.

208.Villalba R, Lee H, Raju DV and Smith Y (2007) Dopaminergic denervation and spine loss in the striatum of MPTP-treated monkeys. IBAGS IXth Proceedings, Abstr P-143, p. 141.

209.Sciamanna G, Bonsi P, Vita D, Taddone A, Platania P, Mitrano DA, Bernardi G, Smith Y and Pisani A (2007) Functional and ultrastructural analysis of group I mGluR in striatal fast-spiking interneurons. IBAGS IXth Proceedings, Abstr P-109, p. 122.

210. Jin X, Y Smith (2008) Activity dependent modulation of GAT-1 and GAT-3 on GABAergic transmission in the rat globus pallidus. Soc Neurosci Abstr 135.15.

211. Hadipour-Niktarash A, H. Lee, ZU Khan, Y Smith and T Wichmann (2008) Effects of D2-like dopamine receptor activation on neuronal activity in substantis nigra pars reticulata and globus pallidus in monkeys. Soc Neurosci Abstr 274.1.

212. Galvan A, X Hu, J Blesa, Y Smith and T Wichmann (2008) Altered functions of GABA transporters in the globus pallidus of parkinsonian monkeys. Soc Neurosci Abstr 578.3

213. Villalba RM, Y Smith (2008) Plasticity of vGluT1-containing axo-spinous synapses in the striatum of MPTP-treated parkinsonian monkeys: A 3D ultrastructural analysis. Soc Neurosci Abstr 726.10

214. Rommelfenger KS, Y Smith and D Weinshenker (2008) Alpha-1 adrenergic receptor subcellular localization in the rat striatum and midbrain. Soc Neurosci Abstr 726.10.

215. Bogenpohl J, J Pare, Y Smith (2008) Subcellular localization of the adenosine A2A receptor in the monkey basal ganglia. Soc Neurosci Abstr 825.23.

216. Masilamoni, G., J. Votaw, L. Howell, J. Bogenpohl, T. Wichmann and Y. Smith (2009) In vivo assessment of degeneration of the nigrostriatal dopaminergic tract in MPTP-treated monkeys with 18F-FECNT positron emission tomography. Mov. Disorders 24 (Suppl 1): S363.

217. Masilamoni, G., D. Alagille, V. Reddy, K. Delevich, J. Bogenpohl, J. Votaw, G. Tamagnan, T. Wichmann and Y. Smith (2009) Potential neuroprotective effects of metabotropic glutamate receptor type 5 (mGluR5) antagonist in MPTP-treated monkeys. Mov. Disorders 24 (Suppl 1): S364.

218. Jin, X and Y. Smith (2009) GABA transporters modulate glutamatergic transmission in the rat globus pallidus. Soc. Neurosci Abstr 134.18.

219. Mitrano, DA, Y Smith and D Weinshenker (2009) Subsynaptic localization of alpha-1 adrenergic receptors in the mesolimbic reward pathway. Soc. For Neurosci. Abstr. 231.15.

220.Smith, Y, GM Jeyaraj, J Votaw, L Howell, T Wichmann (2009) Reproducibility and validity of dopamine transporter PET imaging ligand 18F-FECNT in MPTP-treated monkeys. Soc for Neurosci Abstr 586.8.

221.Mathai, A, JF Pare, S Jenkins, Y Smith (2009) Glutamatergic inputs to the subthalamic nucleus: A quantitative analysis of the synaptic microcircuitry of vGluT1- and vGluT2-containing terminals in nonhuman primates. Soc for Neurosci Abstr 828.2.

223.Pare, JF and Y. Smith (2009) Functional segregation of basal ganglia circuits through the lateral habenula in primates. Soc for Neurosci Abstr 828.3.

224.Gonzales KK, JF Pare, S Jenkins, T Wichmann and Y Smith (2009) Intrinsic microcircuitry of GABAergic inputs from direct and indirect striatofugal neurons on striatal cholinergic interneurons in the primate putamen. Soc for Neurosci Abstr 828.4

225.Masilamoni, G., D. Alagille, J. Bogenpohl, K. Delevich, V. Reddy, JR Votaw, G Tamagnan, A Galvan, T Wichmann and Y Smith (2009) Potential neuroprotective effects of metabotropic glutamate receptor 5 antagonist in MPTP-treated parkinsonian monkeys. Soc for Neurosci Abstr 828.17.

226.Villalba, RM and Y Smith (2009) A comparative 3D ultrastructural analysis of corticostriatal and thalamostriatal axo-spinous synapses in control and MPTP-treated monkeys. Soc for Neurosci Abstr 845.4.

227.Mathai, A., JF Pare, S Jenkins and Y. Smith (2010) Glutamatergic inputs to the subthalamic nucleus: A quantitative analysis of the synaptic microcircuitry of vGluT1- and vGluT2-containing terminals in normal and parkinsonian nonhuman primates. IBAGS X Abstr P-28.

228.Gonzales, KK, JF Pare, S Jenkins, T Wichmann and Y Smith (2010) Striatal cholinergic interneurons receive intrinsic GABAergic inputs from axon collaterals of direct and indirect striatofugal neurons in the primate putamen. IBAGS X Abstr P-61.

229.Rommelfanger KS, A Galvan, MA Kliem, ZU Khan, Y Smith and T Wichmann (2010) Subcellular localization and functional effects of dopamine receptors in the primate subthalamic nucleus. IBAGS X Abstr P-89.

230.Villalba RM, JF Pare and Y Smith (2010) Ultrastructural plasticity of glutamatergic corticostriatal and thalamostriatal axospinous synapses in parkinsonian monkeys. IBAGS X Abstr P-92.

231.Jin, X. and Y. Smith (2010) GAT-3 modulates GABA-A receptor-mediated inhibition in the rat globus pallidus. IBAGS X Abstr P-133.

232.Galvan, A., X. Hu, Y Smith and T Wichmann (2010) Localization and function of GABA-B receptors in the globus pallidus of normal and parkinsonian monkeys. IBAGS X Abstr P-146.

233.Bogenpohl, J., A. Galvan, X. Hu, T. Wichmann and Y. Smith (2010) Electrophysiological and behavioral effects of group III mGluR agonists in MPTP-treated parkinsonian monkeys. FENS meeting, Amsterdam.