contact us

	Xing Hu I was born on the east coast of China in Shanghai, one of the biggest cities in the world. I attended Shanghai Jiao Tong University School of Medicine and received my M.D. degree in 1988. I finished my residency training at RenJi Hospital, which is affiliated with Shanghai Jiao Tong University School of Medicine. I received the Outstanding Resident Award in 1992 and was promoted to Chief Resident. In 1994, I started clinical practices as an attending physician and Assistant Professor in the Division of Gerontology, Department of Medicine in RenJi Hospital. In 2000, my family and I emigrated from Shanghai, China to a small southern town, named Mobile in Alabama, USA. At that time, I started my basic medical research career. I was a Research Trainee in the lab of US Food and Drug Administration. One year later, I moved to Atlanta and got my first basic medical research job in the Department of Pathology at Emory University. In 2002, I worked in the Microarray Core Facility in the Cardiovascular Research Institute at Morehouse School of Medicine, mainly doing gene chips for hypertension and diabetes. Besides being a key person in core facility, I also did work on other studies, especially the Notch gene signaling pathway. We found Notch plays a very important role in vascular pathophysiology. In 2006, I moved back to Emory University as a Research Specialist (Lead) in Dr. Thomas Wichmann’s lab at Yerkes National Primate Center. In this lab, I switched my research from molecular biology to non-human primate neuron electrophysiology and behavior study. I am currently involved in different research projects in the labs of Drs. Yoland Smith and Thomas Wichmann. Using different approaches, including electrophysiology, immunohistochemistry and electron microscope, I work closely with Dr. Adriana Galvan to study the localization and function of GABA-B receptors in Parkinsonian non-human primates in Dr.Wichmann’s lab. Honors and Awards 1985-1986 Outstanding Student Scholarship Awards, 3rd place, School of Medicine, Shanghai Jiao Tong University, China 1992 Excellent Resident Award, Ren Ji Hospital affiliated to Shanghai Jiaotong University School of Medicine, China 2008 One Award, Neurology Department, Emory University SELECTED PEER-REVIEWED PUBLICATIONS **X Hu, Q Zhu, H Lu, Y Xu. Studies of the T-lymphocytes chemotaxis in tumor patients. Shanghai Journal of Immunology 1995;15(2): 100** X Hu, H Lu. Pathogenic analysis of lower digestive tract bleeding in elder patients. Chinese Journal of Clinic 2000;(4):15 Y Zhu, H Lu, N Fang, D Zheng, X Hu. Analysis of blood lipid in 1089 cases of pre-elder and elder male.Chinese Journal of Gerontology 2000;20(4):215-217. W Wang, CZ Prince, X Hu, MJ Pollman. HRT1 modulates vascular smooth muscle cell proliferation and apoptosis. Bioch Biophys Res Commun. 2003;308(3):596-601 J Zhang, W Zhong, T Cui, X Hu, K Xu, C Xie, C Xue, G Gibbons, YE. Chen, M Yang, L Li, C Liu. Generation of an adult smooth muscle cell–targeted Cre recombinase mouse model. Arterioscler Thromb Vasc Biol. 2006;26(3):e23-4. *D Liu, J Hou, X Hu, X Wang, Y Xiao, H DeLeon. Neuronal chemorepellent Slit2 inhibits vascular smooth muscle cell migration by suppressing small GTPase Rac1 activation. Circ Res* 2006;98 (4):480-9. Galvan, A., X. Hu, Y. Smith and T. Wichmann. Localization and function of GABA transporters in the globus pallidus of parkinsonian monkeys. Exptl Neurology 2010;223: 505-515. PMID 20138865. Abstracts** Wang W, Hu X, Prince CZ, Paniagua OA, and Pollman MJ. The Notch3 Signaling Pathway is Modulated During the Induction and Regression of Hypertension-Induced Vascular Remodeling. Circulation 2002;106:II-117. Wang W, Hu X, Prince CZ, and Pollman MJ. Notch3 Signaling Promotes Vascular Smooth Muscle Cell (VSMC) Hypertrophy: Modulation of Transforming Growth Factor-beta1 (TGF-beta1). Circulation 2002;106:II-216. Wang W, Wang G, Prince CZ, Hu X, and Pollman MJ. Notch 3 Functions as a Critical Vascular Smooth Cell (VSMC) Fate Determinant through Novel Downstream Target Genes Identified via Transcriptional Profiling. Circulation 2002;106:II-209. Hou J, Prince CZ, Hu X, Wang G, Pollman MJ, and Wang W. Notch2 functions as a critical vascular smooth muscle cell (VSMC) fate determinant: modulation of p27kip1 and Akt. Second Asia Pacific Scientific Forum, June 8-10,2003. Galvan, A, Hu X, Smith Y and Wichmann T (2007) Changes in the subcellular localization and functions of GABA-B receptors in the globus pallidus of MPTP-treated monkeys. IBAGS IXth Proceedings, Abstr P-061, p. 95. Galvan A, X Hu, J Blesa, Y Smith and T Wichmann (2008) Altered functions of GABA transporters in the globus pallidus of parkinsonian monkeys. Soc Neurosci Abstr 578.3 Galvan, A., B. Nanda, X. Hu, Y. Smith and T. Wichmann (2009) Changes in the subcellular localization and functions of GABA-B receptors in the globus pallidus of MPTP-treated monkeys. In Groenewegen HJ et al (eds), The Basal Ganglia IX, Springer: New York, pp. 387-397 Bogenpohl, J., A. Galvan, X. Hu, T. Wichmann and Y. Smith (2010) Electrophysiological and behavioral effects of group III mGluR agonists in MPTP-treated parkinsonian monkeys. FENS meeting, Amsterdam. Galvan, A., X. Hu, Y Smith and T Wichmann (2010) Localization and function of GABA-B receptors in the globus pallidus of normal and parkinsonian monkeys. IBAGS X Abstr P-146. Ma, Y., Hu, X., Jinnah, H.A., Galvan, A., Smith, Y., Wichmann, T. (2010) Induction of abnormal movements by MPTP treatment in infant rhesus monkeys. Society for Neurosciences.

Xing Hu

I was born on the east coast of China in Shanghai, one of the biggest cities in the world. I attended Shanghai Jiao Tong University School of Medicine and received my M.D. degree in 1988. I finished my residency training at RenJi Hospital, which is affiliated with Shanghai Jiao Tong University School of Medicine. I received the Outstanding Resident Award in 1992 and was promoted to Chief Resident. In 1994, I started clinical practices as an attending physician and Assistant Professor in the Division of Gerontology, Department of Medicine in RenJi Hospital.

In 2000, my family and I emigrated from Shanghai, China to a small southern town, named Mobile in Alabama, USA. At that time, I started my basic medical research career. I was a Research Trainee in the lab of US Food and Drug Administration. One year later, I moved to Atlanta and got my first basic medical research job in the Department of Pathology at Emory University. In 2002, I worked in the Microarray Core Facility in the Cardiovascular Research Institute at Morehouse School of Medicine, mainly doing gene chips for hypertension and diabetes. Besides being a key person in core facility, I also did work on other studies, especially the Notch gene signaling pathway. We found Notch plays a very important role in vascular pathophysiology.

In 2006, I moved back to Emory University as a Research Specialist (Lead) in Dr. Thomas Wichmann’s lab at Yerkes National Primate Center. In this lab, I switched my research from molecular biology to non-human primate neuron electrophysiology and behavior study. I am currently involved in different research projects in the labs of Drs. Yoland Smith and Thomas Wichmann. Using different approaches, including electrophysiology, immunohistochemistry and electron microscope, I work closely with Dr. Adriana Galvan to study the localization and function of GABA-B receptors in Parkinsonian non-human primates in Dr.Wichmann’s lab.

Honors and Awards

1985-1986     Outstanding Student Scholarship Awards, 3rd place, School of Medicine, Shanghai Jiao Tong University, China

1992                 Excellent Resident Award, Ren Ji Hospital affiliated to Shanghai Jiaotong University School of Medicine, China

2008                One Award, Neurology Department, Emory University

SELECTED PEER-REVIEWED PUBLICATIONS

X Hu, Q Zhu, H Lu, Y Xu. Studies of the T-lymphocytes chemotaxis in tumor patients. Shanghai Journal of Immunology 1995;15(2): 100

X Hu, H Lu. Pathogenic analysis of lower digestive tract bleeding in elder patients. Chinese Journal of Clinic 2000;(4):15

Y Zhu, H Lu, N Fang, D Zheng, X Hu. Analysis of blood lipid in 1089 cases of pre-elder and elder male.Chinese Journal of Gerontology 2000;20(4):215-217.

W Wang, CZ Prince, X Hu, MJ Pollman. HRT1 modulates vascular smooth muscle cell
proliferation and apoptosis. Bioch Biophys Res Commun. 2003;308(3):596-601

J Zhang, W Zhong, T Cui, X Hu, K Xu, C Xie, C Xue, G Gibbons, YE. Chen, M Yang, L Li, C Liu. Generation of an adult smooth muscle cell–targeted Cre recombinase mouse model. Arterioscler Thromb Vasc Biol. 2006;26(3):e23-4.

D Liu, J Hou, X Hu, X Wang, Y Xiao, H DeLeon. Neuronal chemorepellent Slit2 inhibits vascular smooth muscle cell migration by suppressing small GTPase Rac1 activation. Circ Res 2006;98 (4):480-9.

Galvan, A., X. Hu, Y. Smith and T. Wichmann. Localization and function of GABA transporters in the globus pallidus of parkinsonian monkeys. Exptl Neurology 2010;223: 505-515. PMID 20138865.

Abstracts

Wang W, Hu X, Prince CZ, Paniagua OA, and Pollman MJ. The Notch3 Signaling Pathway is Modulated During the Induction and Regression of Hypertension-Induced Vascular Remodeling. Circulation 2002;106:II-117.

Wang W, Hu X, Prince CZ, and Pollman MJ. Notch3 Signaling Promotes Vascular Smooth Muscle Cell (VSMC) Hypertrophy: Modulation of Transforming Growth Factor-beta1 (TGF-beta1). Circulation 2002;106:II-216.

Wang W, Wang G, Prince CZ, Hu X, and Pollman MJ. Notch 3 Functions as a Critical Vascular Smooth Cell (VSMC) Fate Determinant through Novel Downstream Target Genes Identified via Transcriptional Profiling. Circulation 2002;106:II-209.

Hou J, Prince CZ, Hu X, Wang G, Pollman MJ, and Wang W. Notch2 functions as a
critical vascular smooth muscle cell (VSMC) fate determinant: modulation of p27kip1 and Akt. Second Asia Pacific Scientific Forum, June 8-10,2003.

Galvan, A, Hu X, Smith Y and Wichmann T (2007) Changes in the subcellular localization and functions of GABA-B receptors in the globus pallidus of MPTP-treated monkeys. IBAGS IXth Proceedings, Abstr P-061, p. 95.

Galvan A, X Hu, J Blesa, Y Smith and T Wichmann (2008) Altered functions of GABA transporters in the globus pallidus of parkinsonian monkeys. Soc Neurosci Abstr 578.3

Galvan, A., B. Nanda, X. Hu, Y. Smith and T. Wichmann (2009) Changes in the subcellular localization and functions of GABA-B receptors in the globus pallidus of MPTP-treated monkeys. In Groenewegen HJ et al (eds), The Basal Ganglia IX, Springer: New York, pp. 387-397

Bogenpohl, J., A. Galvan, X. Hu, T. Wichmann and Y. Smith (2010) Electrophysiological and behavioral effects of group III mGluR agonists in MPTP-treated parkinsonian monkeys. FENS meeting, Amsterdam.

Galvan, A., X. Hu, Y Smith and T Wichmann (2010) Localization and function of GABA-B receptors in the globus pallidus of normal and parkinsonian monkeys. IBAGS X Abstr P-146.

Ma, Y., Hu, X., Jinnah, H.A., Galvan, A., Smith, Y., Wichmann, T. (2010) Induction of abnormal movements by MPTP treatment in infant rhesus monkeys. Society for Neurosciences.