Malignant hypertension and MAHA (Microangiopathic hemolytic anemia)

06/11/01 (Brown)

 

Re: 59 y/o AAM presenting with malignant hypertension, renal failure, and schistocytosis.

 

Question: The association between malignant hypertension and MAHA

 

     

<1> UI: 66060484 / PMID: 5900775

Annals of Internal Medicine. 64(1):128-36, 1966 Jan.

Malignant hypertension and red cell fragmentation syndrome. Report of a case.

<2> UI: 79220995 / PMID: 379556

Medical Hypotheses. 5(4):453-62, 1979 Apr.

The possible role of hypertension in aggravating hemolytic episodes in G-6PD deficient persons. [Review] [57 refs]

<3> UI: 76217984 / PMID: 132546

Japanese Heart Journal. 17(2):258-64, 1976 Mar.

Malignant hypertension and microangiopathic hemolytic anemia.

<4> UI: 76073339 / PMID: 1059805

Kidney International - Supplement. :S252-61, 1975 Sep.

Abnormalities of coagulation and the development of malignant phase hypertension.

<5> UI: 73250161 / PMID: 4729850

British Heart Journal. 35(8):863, 1973 Aug.

Microangiopathic haemolytic anaemia in malignant phase hypertension.

<6> UI: 73208889 / PMID: 4715145

British Journal of Haematology. 24(4):503-10, 1973 Apr.

The significance of microangiopathic haemolytic anaemia in accelerated hypertension.

<7> UI: 71283124 / PMID: 5568228

Circulation Research. 28(5):Suppl 2:127-42, 1971 May.

Microangipathic hemolytic anemia and the development of the malignant phase of hypertension.

<8> UI: 71060880 / PMID: 5488551

Naika - Internal Medicine. 26(6):1125-33, 1970 Dec.

[Microangiopathic hemolytic anemia associated with malignant hypertension--2 cases and literature review]. [Japanese]

<9> UI: 69254497 / PMID: 4184125

Lancet. 2(7614):266, 1969 Aug 2.

Microangiopathic haemolytic anaemia and malignant hypertension.

<10> UI: 68397798 / PMID: 5672852

Blood. 32(2):278-91, 1968 Aug.

Microangiopathic hemolytic anemia in rats with malignant hypertension.

<11> UI: 66060484 / PMID: 5900775

Annals of Internal Medicine. 64(1):128-36, 1966 Jan.

Malignant hypertension and red cell fragmentation syndrome. Report of a case.

 

 

<1>

Unique Identifier: 66060484 / PubMed Identifier: 5900775

Authors: Capelli JP. Wesson GL Jr. Erslev AV.

Title: Malignant hypertension and red cell fragmentation syndrome. Report of a case.

Source: Annals of Internal Medicine. 64(1):128-36, 1966 Jan.

 

 

<2>

Unique Identifier: 79220995 / PubMed Identifier: 379556

Authors: Moore GS. Calabrese EJ.

Title: The possible role of hypertension in aggravating hemolytic episodes in G-6PD deficient persons. [Review] [57 refs]

Source: Medical Hypotheses. 5(4):453-62, 1979 Apr.

Abstract: Approximately 13 percent of American Negro males carry a mutant [A-variant] glucose-6-phosphate dehydrogenase enzyme in their red blood cells that predisposes them to hemolytic episodes following exposure to oxidant drugs such as primaquine. Most hemolytic episodes to standard prophylactic treatment are mild and self-limited, but as many as 2 percent of Negro males develop severe hemolysis when similarly treated. The exaggerated response may be due in part to the combination of G-6-PD deficiency and hypertension since hypertension can cause red cell fragmentation, and the stressed cells of G-6-PD deficient person would be more sensitive to such fragmentation. [References: 57]

 

 

<3>

Unique Identifier: 76217984 / PubMed Identifier: 132546

Authors: Otsuka Y. Abe K. Sato Y. Saito T. Irokawa N.

Title: Malignant hypertension and microangiopathic hemolytic anemia.

Source: Japanese Heart Journal. 17(2):258-64, 1976 Mar.

Abstract: The fourth case found in Japan manifesting the features of malignant hypertension and microangiopathic hemolytic anemia (MHA) was reported. In this case, bilateral nephrectomy brought down the blood pressure and relieved MHA. The patient has since been maintained alive and well on hemodialysis up to the time of this report.

 

 

<4>

Unique Identifier: 76073339 / PubMed Identifier: 1059805

Authors: Gavras H. Oliver N. Aitchison J. Begg C. Briggs JD. Brown JJ. Horton PW. Lee F. Lever AF. Prentice C. Robertson JI.

Title: Abnormalities of coagulation and the development of malignant phase hypertension.

Source: Kidney International - Supplement. :S252-61, 1975 Sep.

 

 

<5>

Unique Identifier: 73250161 / PubMed Identifier: 4729850

Authors: Oliver N. Gavras H. Aitchison J. Begg C. Briggs JD. Brown JJ. Horton PW. Lee F. Lever AF. Prentice C. Robertson JI.

Title: Microangiopathic haemolytic anaemia in malignant phase hypertension.

Source: British Heart Journal. 35(8):863, 1973 Aug.

 

 

<6>

Unique Identifier: 73208889 / PubMed Identifier: 4715145

Authors: Sevitt LH. Naish P. Baker LR. Bulpitt CJ. Archer DF. Nelson DA. Peters DK.

Title: The significance of microangiopathic haemolytic anaemia in accelerated hypertension.

Source: British Journal of Haematology. 24(4):503-10, 1973 Apr.

 

 

<7>

Unique Identifier: 71283124 / PubMed Identifier: 5568228

Authors: Gavras H. Brown WC. Brown JJ. Lever AF. Linton AL. MacAdam RF. McNicol GP. Robertson JI. Wardrop C.

Title: Microangipathic hemolytic anemia and the development of the malignant phase of hypertension.

Source: Circulation Research. 28(5):Suppl 2:127-42, 1971 May.

 

 

<8>

Unique Identifier: 71060880 / PubMed Identifier: 5488551

Authors: Kariya T. Konuma S. Ohashi T. Yoshitoshi Y.

Title: [Microangiopathic hemolytic anemia associated with malignant hypertension--2 cases and literature review]. [Japanese]

Source: Naika - Internal Medicine. 26(6):1125-33, 1970 Dec.

 

 

<9>

Unique Identifier: 69254497 / PubMed Identifier: 4184125

Authors: Kincaid-Smith P.

Title: Microangiopathic haemolytic anaemia and malignant hypertension.

Source: Lancet. 2(7614):266, 1969 Aug 2.

 

 

<10>

Unique Identifier: 68397798 / PubMed Identifier: 5672852

Authors: Venkatachalam MA. Jones DB. Nelson DA.

Title: Microangiopathic hemolytic anemia in rats with malignant hypertension.

Source: Blood. 32(2):278-91, 1968 Aug.

 

 

<11>

Unique Identifier: 66060484 / PubMed Identifier: 5900775

Authors: Capelli JP. Wesson GL. Erslev AV.

Title: Malignant hypertension and red cell fragmentation syndrome. Report of a case.

Source: Annals of Internal Medicine. 64(1):128-36, 1966 Jan.

 

 

 

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