Volume 5, Number 25; March 09, 2006
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Volume 5, Number 25; March 09, 2006 |
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Middle-aged female with pulmonary hypertension, swollen leg, and Bell's Palsy.
Recommended reading:
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Patient: 53 year old female being evaluated for pulmonary hypertension. Presenting with 10 months enormously swollen leg after cat bite, 3 months Bell's Palsy, current SOB.
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Session Handout:
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Clinical Question: 1) Is there any association between Bell's Palsy and lymphangitic spread of cancer?
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Readings:
Link Directly to Fulltext Article at Science Direct <10> Unique Identifier [PMID]: 3990335 Authors: Cartwright RA. Boddy J. Barnard D. Bernard S. Bird CC. Roberts BE. Richards ID. Title: Association between Bell's palsy and lymphoid malignancies.
Source: Leukemia Research. 9(1):31-3, 1985. Abstract: Eight cases of lymphoid malignancy preceded by Bell's palsy are reported. There was a disproportionate number of ALL cases, two of which were of T-cell type. The possible pathogenic association of these conditions is discussed. Publication Type: Journal Article.
Link Directly to Fulltext Article at Publisher <1> Unique Identifier [PMID]: 12601494 Authors: Ozcakar L. Akinci A. Ozgocmen S. Aksu S. Cetin E. Institution: Department of Physical Medicine and Rehabilitation, Hacettepe University Medical School, Ankara, Turkey. Title: Bell's palsy as an early manifestation of acute lymphoblastic leukemia.
Source: Annals of Hematology. 82(2):124-6, 2003 Feb. Abstract: A 20-year-old man with the complaints of malaise, fever, and tooth gum bleeding presented at a hospital. He was found to have generalized lymphadenopathy, thrombocytopenia, and leukocytosis. Ensuing bone marrow biopsy led to a diagnosis of acute lymphoblastic leukemia (ALL). He also had a sense of "facial stretching" and difficulty during eating. After clinical examination, he was diagnosed with right-sided peripheral type facial nerve paralysis (Bell's palsy). The magnetic resonance imaging studies demonstrated bilateral facial nerve involvement, predominantly on the right side. The patient received steroid treatment and local facial radiotherapy for Bell's palsy. A concurrent facial exercise program was ordered. Seemingly a less significant diagnosis in a leukemia patient, we considered our case notable since an ALL patient presenting with Bell's palsy, especially at the very beginning of the disease, is not that common. The cases of relapsing ALL reported in the literature initially presenting with the same scenario further strengthen the significance. Publication Type: Case Reports. Journal Article.
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Resident Report / Department of Medicine & Grady Branch Library Emory University School of Medicine 2005 Edition Participating Faculty: Carlos Del Rio MD / Joyce Doyle MD / Lorenzo Difrancesco MD / Erich Folch MD / Alicia Hidron MD
Contact:
Karl Woodworth
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