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Volume 8, Number 41; November 29, 2007 Nausea / Vomiting - Cortisol Levels |
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Clinical Question:
1) What could be a cause of high cortisol levels with persistent nausea / vomiting?
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Session Handout:
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Readings:
<4> Unique Identifier [PMID]: 16945594 Authors: Otto B. Riepl RL. Klosterhalfen S. Enck P. Institution: Medical Department-Innenstadt, University Hospitals of Munich, Ziemssenstr. 1, D-80336 Munich, Germany. Baerbel.Otto@med.uni-muenchen.de Title: Endocrine correlates of acute nausea and vomiting. [Review] [17 refs]
Source: Autonomic Neuroscience-Basic & Clinical. 129(1-2):17-21, 2006 Oct 30. Abstract: This paper gives an overview of studies investigating endocrine changes in acute nausea and vomiting. The aetiology of nausea and vomiting is not fully understood, but it has been shown that different stress hormones are released into circulation during motion sickness. Studies with animals and humans have shown that acute nausea activates the hypothalamo-pituitary-adrenal axis and the neurohypophyseal system. So-called stress hormones, like adrenocorticotropic hormone, cortisol, and antidiuretic hormone, are released concomitant with nausea and vomiting in motion sickness, but do not seem to be involved in the aetiology of motion sickness. Nevertheless, plasma levels of stress hormones more or less correlate to the intensity of nausea related symptoms. Although gastroenteropancreatic hormones are involved in gastrointestinal motility, there are only few data describing their changes in response to acute nausea or vomiting. [References: 17] Publication Type: Journal Article. Research Support, Non-U.S. Gov't. Review.
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Resident Report / Department of Medicine & Grady Branch Library Emory University School of Medicine 2007 Edition Participating Faculty: Carlos Del Rio MD / Joyce Doyle MD / Lorenzo Difrancesco MD / Rachel Del Favero MD / Lewis Satterwhite MD
Contact:
Karl Woodworth
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