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Unique Identifier 91289906
Authors: Adamick RD. Gleckel LC. Graver LM.
Institution: Albert Einstein College of Medicine, Harris Chasanoff Heart Institute, Long Island Jewish Medical Center.
Title: Acute thrombosis of an aortic bioprosthetic valve: transthoracic and transesophageal echocardiographic findings.
Source: American Heart Journal. 122(1 Pt 1)241-2, 1991 Jul.
Abstract: To assess the reported association between colonic angiodysplasia and aortic stenosis, we performed a quantitative and methodologic analysis of the literature. In four controlled studies that support an association between aortic stenosis and idiopathic gastrointestinal bleeding there are major methodologic deficiencies including the following: nonblinded data collection, noncomparable diagnostic examination, nonblinded ascertainment of exposure, and noncomparable demographic susceptibility. None of the studies directly assesses angiodysplasia. Additional case reports about aortic valve replacement used to treat bleeding from angiodysplasia are limited in number and in duration of follow-up. We conclude that the existing literature does not demonstrate an association between aortic stenosis and angiodysplasia. Further controlled evaluation of this topic would be useful. [References: 33]

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Unique Identifier 91053408
Authors: Baciewicz PA. del Rio C. Goncalves MA. Lattouf OM. Guyton RA. Morris DC.
Institution: Crawford Long Hospital, Emory University, Atlanta, GA 30365.
Title: Catastrophic thrombosis of porcine aortic bioprostheses.
Source: Annals of Thoracic Surgery. 50(5)817-9, 1990 Nov.
Abstract: Hemodynamically critical thrombotic stenosis of porcine bioprosthetic valves in the aortic position without thrombotic predisposition is rare. Two patients at our institution abruptly manifested thrombotic stenosis of porcine bioprosthetic valves in the aortic position within 3 months of implantation without apparent predisposing factors. Clinicians should consider this rare but catastrophic complication in the appropriate setting.

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