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Unique Identifier 97210932
Authors: Soderdahl DW. Thrasher JB. Hansberry KL.
Institution: Urology Service, Madigan Army Medical Center, Tacoma, WA 98431-5000, USA.
Title: Bilateral renal cell carcinoma in autosomal dominant polycystic kidney disease. A case report and literature review. [Review] [24 refs]
Source: American Journal of Nephrology. 17(1)96-9, 1997.
Abstract: The association of autosomal dominant polycystic kidney disease with renal cell carcinoma is infrequent. A case of bilateral renal cell carcinoma in conjunction with autosomal dominant polycystic kidney disease is presented. The discussion emphasizes pertinent diagnostic and therapeutic considerations. [References: 24]

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Unique Identifier 94337150
Authors: Bretan PN Jr.
Institution: Department of Surgery and Urology, School of Medicine, University of California at San Francisco 94143-0116.
Title: Acquired renal cystic disease: is there a need for screening for renal cell carcinoma in patients with renal failure?. [Review] [20 refs]
Source: Seminars in Urology. 12(2)89-92, 1994 May.
Abstract: OBJECTIVE--This article reviews the incidence of arterial thromboembolism in patients with heart failure who are not receiving anticoagulants. We also examine whether more severe ventricular dysfunction increases this incidence and the efficacy and risks of anticoagulation for patients in sinus rhythm. DATA SOURCES--English-language studies referenced in MEDLINE or EMBASE (January 1966 to September 1993) were reviewed. We used the search terms heart failure, congestive; congestive heart failure; heart failure; cardiac failure; and dilated cardiomyopathy in conjunction with the terms anticoagulation, cerebrovascular disorders, stroke, and thromboembolism. STUDY SELECTION--All studies with separate data for patients with chronic heart failure not receiving anticoagulants were included. Articles addressing valvular heart disease or heart failure secondary to acute myocardial infarction or Chagas' disease were excluded. Studies of the occurrence of left ventricular mural thrombi were also reviewed. DATA EXTRACTION AND SYNTHESIS--Inclusion and exclusion criteria, prevalence of atrial fibrillation, mean follow-up, and the occurrence of arterial thromboembolic events were extracted. If the incidence was not given, this was estimated using the proportion of patients with events divided by the mean follow-up. CONCLUSION--The incidence of arterial thromboembolism ranged from 0.9 to 5.5 events per 100 patient-years, with the largest studies reporting incidence of 2.0% and 2.4%. Findings regarding the relationship between ventricular function and thromboembolic events are contradictory. No controlled trial has assessed the efficacy or risks of anticoagulation for patients with heart failure and sinus rhythm, and reported efficacy in case series ranged from 0% to 100%. Until adequate studies are performed, anticoagulation should be discouraged for patients with heart failure who are in sinus rhythm.

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Unique Identifier 94027023
Authors: Chapman AB. Johnson AM. Gabow PA.
Institution: Department of Medicine, University of Colorado Health Sciences Center, Denver 80262.
Title: Intracranial aneurysms in patients with autosomal dominant polycystic kidney disease: how to diagnose and who to screen. [Review] [30 refs]
Source: American Journal of Kidney Diseases. 22(4)526-31, 1993 Oct.
Abstract: This is the era of polypharmacy. Treatment with multiple therapeutic agents for multiple underlying medical conditions leads to greater vulnerability to such metabolic imbalances as hyperkalemia. The physician must know which underlying medical conditions and drugs predispose to abnormal intracellular-extracellular potassium balance and abnormal regulation of potassium excretion. [References: 0]

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