Sickle Cell Disease - Neurological Complications
5/03/00 (Del Rio)
Group: Wednesday Residents
Group: Wednesday Residents
RE: A young African-American male with SC disease who collapsed after running.
Question: What neurological complications are found in patients with sickle cell disease?
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Unique Identifier: 84127458
Authors: Fabian RH. Peters BH.
Title: Neurological complications of hemoglobin SC disease.
Source: Archives of Neurology. 41(3):289-92, 1984 Mar.
Abstract: The records of 68 patients with hemoglobin SC disease and 68 age- and sex-matched control patients were reviewed: for neurological problems. A significant increase in retinopathy, stupor/coma, and seizures was noted in the hemoglobin: SC group. Hemiplegia, noted in two young patients, was probably also secondary to hemoglobin SC disease.: Hemoglobin SC disease may often go unrecognized as a cause of stupor and coma in older patients without other: obvious manifestations of a sickling hemoglobinopathy. Factors known to precipitate sickling crisis and the associated: neurological complications should be avoided, especially in patients undergoing surgery or parturition.
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