Erythrocyte Sedimentation Rate (ESR)

12/20/99 (Doyle)

Question: Is the erythrocyte sedimentation rate a useful tool in diagnosis?

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Unique Identifier: 85248515

Authors: Bedell SE. Bush BT.

Abstract: The erythrocyte sedimentation rate is a simple, inexpensive laboratory test that clinicians have used for decision-making for over 50 years. Despite this fact, many criticize the test because of its lack of specificity and because the concept of erythrocyte sedimentation rate as a "sickness index" seems scientifically unsound. This review discusses the physical and chemical properties that govern red blood cell sedimentation, how sedimentation is measured, and the way in which the erythrocyte sedimentation rate has previously been used to assist in the diagnosis of infectious, inflammatory, or neoplastic disease. The clinical significance, sensitivity, specificity, and predictive value of a low or elevated erythrocyte sedimentation rate are also re-evaluated.

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Unique Identifier: 84044395

Authors: Tsouderos Y. Chretien J. Ryckewaert A.

Abstract: The authors studied the mean ESR and its variations between the ages of 20 and 89 by groups of 5 years in a population considered to be healthy of 20.743 women and 26.462 men. The mean ESR rises with age. In women it is 7.2 mm between 20 and 24 and changes minimally until the age of 45. It rises to 8.9 mm between 50 and 54, 11.6 mm between 70 and 74 and 15.4 mm between 80 and 84. In men, it is lower: 4.1 mm between 20 and 24, 6.1 mm between 50 and 54, 8.8 mm between 70 and 74 and 10.9 mm between 80 and 84.