Our Research
Dr. TJ Murphy is Associate Professor in the Department of Pharmacology and Chemical Biology in the Emory University School of Medicine. His lab studies how receptors modulate several mechanisms of gene expression control. The regulatory targets, genes, and mRNAs we examine are used as models to understand how complex signaling pathway information becomes integrated within cells.
The basic idea is that how an mRNA is induced or suppressed in response to a stimulus depends upon:
- How several different targets of signaling are activated simultaneously.
- Which of these factors assemble to regulate a given gene or mRNA?